An understanding of the diversity of cortical GABAergic interneurons is critical to understand
the function of the cerebral cortex. Recent data suggest that neurons expressing three …

Cellular specialization is particularly prominent in mammalian nervous systems, which are
composed of millions to billions of neurons that appear in thousands of different 'flavors' and …

An intriguing feature of the adult brain is its capacity for structural and functional modification
in response to external stimuli. This plasticity of the adult nervous system has been the …

Alzheimer’s disease (AD) is highly heritable and recent studies have identified over 20
disease-associated genomic loci. Yet these only explain a small proportion of the genetic …

The mammalian cerebral cortex supports cognitive functions such as sensorimotor
integration, memory, and social behaviors. Normal brain function relies on a diverse set of …

The mammalian nervous system executes complex behaviors controlled by specialized,
precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a million …

The primary sensory system requires the integrated function of multiple cell types, although
its full complexity remains unclear. We used comprehensive transcriptome analysis of 622 …

Intelligence is highly heritable 1 and a major determinant of human health and well-being 2
. Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …

Oligodendrocytes have been considered as a functionally homogeneous population in the
central nervous system (CNS). We performed single-cell RNA sequencing on 5072 cells of …

Insomnia is the second most prevalent mental disorder, with no sufficient treatment available.
Despite substantial heritability, insight into the associated genes and neurobiological …