Abstract Comparison of [ 125 I]epibatidine and 5‐[ 125 I]iodo‐3‐(2‐azetidinylmethoxy)pyridine
([ 125 I]A‐85380) autoradiography showed evidence for nicotinic receptor heterogeneity. …

Imaging of glutamate carboxypeptidase II (GCP II), also known as N-acetylated α-linked l-amino
dipeptidase (NAALADase), may enable study of glutamatergic transmission, prostate …

18 F-2β-Carbomethoxy-3β-(4-chlorophenyl)-8-(2-fluoroethyl)nortropane ( 18 F-FECNT), a
PET radioligand for the dopamine transporter (DAT), generates a radiometabolite that enters …

The present study sought to determine whether doses of methamphetamine in the range of
those used recreationally by humans produce brain dopamine (DA) neurotoxicity in baboons …

Peripheral benzodiazepine receptors (PBRs) are upregulated on activated microglia. We
recently developed a promising positron emission tomography (PET) ligand, [ 11 C]PBR28, …

Neuronal nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels found
throughout the central and peripheral nervous systems. They are crucial to normal physiology …

The derivation of dopamine neurons is one of the best examples of the clinical potential of
embryonic stem (ES) cells, but the long-term function of the grafted neurons has not been …

Purpose The purpose of this study was to evaluate the capacity of [ 11 C]6-OH-BTA-1 and
positron emission tomography (PET) to quantify β-amyloid (Aβ) plaques in the Tg2576 mouse …

Carboxylic esters were successfully labeled with one of two short-lived positron-emitters,
carbon-11 or fluorine-18, within a hydrodynamically-driven micro-reactor. The non-radioactive …

This paper presents the first Positron Emission Tomography (PET) images of the serotonin (5‐hydroxytryptamine,
5‐HT) transporter in the living human brain. PET imaging was …