[PDF][PDF] Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells

…, Y Shin, J Shin, N Chang, YT Oh, H Kim, J Rheey… - Cancer cell, 2013 - cell.com
… (H–J) Measurement of subcutaneous xenograft tumor size after treatment with DZNep. Error
… harvested, and processed for immunoblots and co-IP analysis (I) and (J) and IF staining (K). …

[HTML][HTML] FoxM1 promotes stemness and radio-resistance of glioblastoma by regulating the master stem cell regulator Sox2

…, J Rheey, K Shin, YJ Seo, YS Choi, JI Lee, J Lee… - PloS one, 2015 - journals.plos.org
Glioblastoma (GBM) is the most aggressive and most lethal brain tumor. As current standard
therapy consisting of surgery and chemo-irradiation provides limited benefit for GBM …

Wnt/β-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells

…, EH Kim, J Rheey, HJ Jin, Y Lee, KM Joo, J Lee… - Neuro …, 2013 - academic.oup.com
Background Glioblastoma (GBM) is the most lethal and common type of primary brain tumor.
Recent evidence suggests that a subpopulation of GBM cells (glioblastoma stem cells […

3D bioprinted vascularized lung cancer organoid models with underlying disease capable of more precise drug evaluation

Y Choi, H Lee, M Ann, M Song, J Rheey, J Jang - Biofabrication, 2023 - iopscience.iop.org
J Lee and J Jang designed and supervised this project. … [7] Subramanian J et al 2023
Usage of epidermal growth factor mutation testing and impact on treatment patterns in non-small …

Otx2 promotes the survival of damaged adult retinal ganglion cells and protects against excitotoxic loss of visual acuity in vivo

RT Ibad, J Rheey, S Mrejen, V Forster… - Journal of …, 2011 - Soc Neuroscience
… Cg(Thy1-CFP)23Jrs/j mice did not reproduce well in our laboratory, subsequent mouse
mixed culture experiments were performed with C57BL/6 mice and NF immunofluorescence. …

[HTML][HTML] Overexpression of mutant HSP27 causes axonal neuropathy in mice

…, JS Lee, HJ Ahn, N Jung, S Hwang, J Rheey… - Journal of Biomedical …, 2015 - Springer
… In this study, we generated a transgenic mouse (C57BL6/J strain) expressing S135F
mutation in HSP27 to further investigate the clinical aspects and development of therapeutic …

[HTML][HTML] Cell non-autonomous functions of homeoproteins in neuroprotection in the brain

RL Joshi, RT Ibad, J Rheey, F Castagner, A Prochiantz… - FEBS letters, 2011 - Elsevier
Homeoproteins transcription factors can transfer between cells and play important roles in
development. However, some of these homeoproteins are expressed in the adult, but their …

[HTML][HTML] BP1 transcriptionally activates bcl-2and inhibits TNFα-induced cell death in MCF7 breast cancer cells

HS Stevenson, SW Fu, JJ Pinzone, J Rheey… - Breast Cancer …, 2007 - Springer
Introduction We have previously shown that the Beta Protein 1 (BP1) homeodomain protein
is expressed in 81% of invasive ductal breast carcinomas, and that increased BP1 …

[HTML][HTML] Decreased performance in IDUA knockout mouse mimic limitations of joint function and locomotion in patients with Hurler syndrome

C Kim, MJ Kwak, SY Cho, A Ko, J Rheey… - Orphanet Journal of …, 2015 - Springer
Background Mucopolysaccharidosis type I (MPS I) is caused by the deficiency of alpha-L-iduronidase
(IDUA), which is involved in the degradation of glycosaminoglycans (GAGs), such …

Adaptive loss function design algorithm for input data distribution in autoencoder

J Rheey, D Choi, H Park - 2022 13th International Conference …, 2022 - ieeexplore.ieee.org
The training performance of an autoencoder is significantly affected by its loss function. In
order to improve the performance of autoencoders, it is important to design ap-propriate loss …