User profiles for J. Scafidi

Jonathan Scafidi

The University of Edinburgh
Verified email at ed.ac.uk
Cited by 447

Neurobiology of premature brain injury

N Salmaso, B Jablonska, J Scafidi, FM Vaccarino… - Nature …, 2014 - nature.com
Every year in the United States, an estimated 500,000 babies are born preterm (before 37
completed weeks of gestation), and this number is rising, along with the recognition of brain …

Emerging connections between cerebellar development, behaviour and complex brain disorders

A Sathyanesan, J Zhou, J Scafidi, DH Heck… - Nature Reviews …, 2019 - nature.com
The human cerebellum has a protracted developmental timeline compared with the neocortex,
expanding the window of vulnerability to neurological disorders. As the cerebellum is …

Underground hydrogen storage: a review

J Miocic, N Heinemann, K Edlmann, J Scafidi, F Molaei… - 2023 - pubs.geoscienceworld.org
Large-scale underground storage of hydrogen gas is expected to play a key role in the energy
transition and in near future renewable energy systems. Despite this potential, experience …

Hydrogen storage in saline aquifers: The role of cushion gas for injection and production

N Heinemann, J Scafidi, G Pickup, EM Thaysen… - International journal of …, 2021 - Elsevier
Hydrogen stored on a large scale in porous rocks helps alleviate the main drawbacks of
intermittent renewable energy generation and will play a significant role as a fuel substitute to …

[HTML][HTML] Increased vascular permeability in C1 inhibitor–deficient mice mediated by the bradykinin type 2 receptor

…, RC MacFarlane, AN Mulligan, J Scafidi… - The Journal of …, 2002 - Am Soc Clin Investig
Heterozygosity for C1 inhibitor (C1INH) deficiency results in hereditary angioedema.
Disruption of the C1INH gene by gene trapping enabled the generation of homozygous- and …

Intranasal epidermal growth factor treatment rescues neonatal brain injury

J Scafidi, TR Hammond, S Scafidi, J Ritter, B Jablonska… - Nature, 2014 - nature.com
There are no clinically relevant treatments available that improve function in the growing
population of very preterm infants (less than 32 weeks’ gestation) with neonatal brain injury. …

Arg3. 1/Arc mRNA induction by Ca2+ and cAMP requires protein kinase A and mitogen-activated protein kinase/extracellular regulated kinase activation

…, B Dammermann, P Wulff, J Scafidi… - Journal of …, 2001 - Soc Neuroscience
Long-term potentiation (LTP) is a cellular model for persistent synaptic plasticity in the
mammalian brain. Like several forms of memory, long-lasting LTP requires cAMP-mediated …

GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury

M Zonouzi, J Scafidi, P Li, B McEllin, J Edwards… - Nature …, 2015 - nature.com
Diffuse white matter injury (DWMI), a leading cause of neurodevelopmental disabilities in
preterm infants, is characterized by reduced oligodendrocyte formation. NG2-expressing …

[HTML][HTML] The polo‐like protein kinases Fnk and Snk associate with a Ca2+‐and integrin‐binding protein and are regulated dynamically with synaptic plasticity

…, J Scafidi, U Staubli, J Bereiter‐Hahn… - The EMBO …, 1999 - embopress.org
In order to stabilize changes in synaptic strength, neurons activate a program of gene
expression that results in alterations of their molecular composition and structure. Here we …

Experience-dependent regulation of NG2 progenitors in the developing barrel cortex

JM Mangin, P Li, J Scafidi, V Gallo - Nature neuroscience, 2012 - nature.com
We found that, during the formation of the mouse barrel cortex, NG2 cells received
glutamatergic synapses from thalamocortical fibers and preferentially accumulated along septa …