Caloric restriction delays disease onset and mortality in rhesus monkeys
…, SC Johnson, EK Kastman, KJ Kosmatka… - Science, 2009 - science.org
Caloric restriction (CR), without malnutrition, delays aging and extends life span in diverse
species; however, its effect on resistance to illness and mortality in primates has not been …
species; however, its effect on resistance to illness and mortality in primates has not been …
A population-average MRI-based atlas collection of the rhesus macaque
DG McLaren, KJ Kosmatka, TR Oakes, CD Kroenke… - Neuroimage, 2009 - Elsevier
Magnetic resonance imaging (MRI) studies of non-human primates are becoming increasingly
common; however, the well-developed voxel-based methodologies used in human …
common; however, the well-developed voxel-based methodologies used in human …
A calorie-restricted diet decreases brain iron accumulation and preserves motor performance in old rhesus monkeys
…, CL Coe, BB Bendlin, KJ Kosmatka… - Journal of …, 2012 - Soc Neuroscience
Caloric restriction (CR) reduces the pathological effects of aging and extends the lifespan in
many species, including nonhuman primates, although the effect on the brain is less well …
many species, including nonhuman primates, although the effect on the brain is less well …
Rhesus macaque brain morphometry: a methodological comparison of voxel-wise approaches
Voxel-based morphometry studies have become increasingly common in human neuroimaging
over the past several years; however, few studies have utilized this method to study …
over the past several years; however, few studies have utilized this method to study …
Age-related changes in neural volume and microstructure associated with interleukin-6 are ameliorated by a calorie-restricted diet in old rhesus monkeys
…, DG McLaren, E Canu, EK Kastman, KJ Kosmatka… - Neuroimage, 2010 - Elsevier
Systemic levels of proinflammatory cytokines such as interleukin-6 (IL-6) increase in old age
and may contribute to neural atrophy in humans. We investigated IL-6 associations with age …
and may contribute to neural atrophy in humans. We investigated IL-6 associations with age …
Effects of aging and calorie restriction on white matter in rhesus macaques
Rhesus macaques on a calorie restricted diet (CR) develop less age-related disease, have
virtually no indication of diabetes, are protected against sarcopenia, and potentially live …
virtually no indication of diabetes, are protected against sarcopenia, and potentially live …
Homocysteine, neural atrophy, and the effect of caloric restriction in rhesus monkeys
…, DG McLaren, EK Kastman, E Canu, KJ Kosmatka… - Neurobiology of …, 2012 - Elsevier
Higher serum homocysteine (Hcy) levels in humans are associated with vascular pathology
and greater risk for dementia, as well as lower global and regional volumes in frontal lobe …
and greater risk for dementia, as well as lower global and regional volumes in frontal lobe …
[PDF][PDF] IC-P3-198: Memory formation in middle-aged adults: Dynamics of the bold signal across repetitions
…, BB Bendlin, EK Kastman, KJ Kosmatka… - Alzheimer''s and …, 2008 - researchgate.net
Background: 11C PIB PET has been shown to correlate with the presence of brain amyloid
in patients with neurodegenerative disease. The short half-life of 11C makes the clinical use …
in patients with neurodegenerative disease. The short half-life of 11C makes the clinical use …
The relationship between non-steroidal anti-inflammatory (NSAID) use and regional brain volume: a cross-sectional study in cognitively healthy, middle-aged adults.
…, DG McLaren, BM Thiel, ML Ries, KJ Kosmatka… - NeuroImage, 2009 - Elsevier
Methods We performed a voxel-based analysis of the modulated GM and WM probability
maps from high-resolution T1-weighted images, while controlling for age, education, gender, …
maps from high-resolution T1-weighted images, while controlling for age, education, gender, …
Hand Dominance Modulates Interhemispheric Gray Matter Asymmetry in Rhesus Macaques
KJ Kosmatka, EK Kastman, AA Willette, E Canu… - NeuroImage, 2009 - Elsevier
Methods Rhesus macaques were recruited from an ongoing study at the Wisconsin National
Primate Research Center. Hand dominance was assessed by expert observers based on …
Primate Research Center. Hand dominance was assessed by expert observers based on …