[HTML][HTML] Recent advances in the understanding of specific efferent pathways emerging from the cerebellum
…, H Park, Y Yamamoto, K Tanaka-Yamamoto - Frontiers in …, 2021 - frontiersin.org
The cerebellum has a long history in terms of research on its network structures and motor
functions, yet our understanding of them has further advanced in recent years owing to …
functions, yet our understanding of them has further advanced in recent years owing to …
Regulation of cerebellar network development by granule cells and their molecules
M Kim, S Jun, H Park, K Tanaka-Yamamoto… - Frontiers in Molecular …, 2023 - frontiersin.org
The well-organized cerebellar structures and neuronal networks are likely crucial for their
functions in motor coordination, motor learning, cognition and emotion. Such cerebellar …
functions in motor coordination, motor learning, cognition and emotion. Such cerebellar …
[HTML][HTML] Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration
…, JH Shin, Y Yamamoto, K Tanaka-Yamamoto… - Molecular …, 2018 - Springer
Background Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause
of familial and sporadic Parkinson’s disease (PD). Elevated kinase activity is associated …
of familial and sporadic Parkinson’s disease (PD). Elevated kinase activity is associated …
Cerebellar Shank2 regulates excitatory synapse density, motor coordination, and specific repetitive and anxiety-like behaviors
Shank2 is a multidomain scaffolding protein implicated in the structural and functional
coordination of multiprotein complexes at excitatory postsynaptic sites as well as in psychiatric …
coordination of multiprotein complexes at excitatory postsynaptic sites as well as in psychiatric …
VTA-projecting cerebellar neurons mediate stress-dependent depression-like behaviors
…, JS Park, J Kim, Y Yamamoto, K Tanaka-Yamamoto - Elife, 2022 - elifesciences.org
Although cerebellar alterations have been implicated in stress symptoms, the exact contribution
of the cerebellum to stress symptoms remains to be elucidated. Here, we demonstrated …
of the cerebellum to stress symptoms remains to be elucidated. Here, we demonstrated …
[HTML][HTML] Diacylglycerol kinases in the coordination of synaptic plasticity
… Copyright © 2016 Lee, Kim and Tanaka-Yamamoto. This is an open-access article
distributed under the terms of the Creative Commons Attribution License (CC BY). The use, …
distributed under the terms of the Creative Commons Attribution License (CC BY). The use, …
[PDF][PDF] Switching on depression and potentiation in the cerebellum
AR Gallimore, T Kim, K Tanaka-Yamamoto… - Cell reports, 2018 - cell.com
Long-term depression (LTD) and long-term potentiation (LTP) in the cerebellum are important
for motor learning. However, the signaling mechanisms controlling whether LTD or LTP is …
for motor learning. However, the signaling mechanisms controlling whether LTD or LTP is …
[HTML][HTML] Developmental timing-dependent organization of synaptic connections between mossy fibers and granule cells in the cerebellum
T Kim, H Park, K Tanaka-Yamamoto… - Communications …, 2023 - nature.com
The long-standing hypothesis that synapses between mossy fibers (MFs) and cerebellar
granule cells (GCs) are organized according to the origins of MFs and locations of GC axons, …
granule cells (GCs) are organized according to the origins of MFs and locations of GC axons, …
[PDF][PDF] Topographic connectivity and cellular profiling reveal detailed input pathways and functionally distinct cell types in the subthalamic nucleus
H Jeon, H Lee, DH Kwon, J Kim, K Tanaka-Yamamoto… - Cell Reports, 2022 - cell.com
The subthalamic nucleus (STN) controls psychomotor activity and is an efficient therapeutic
deep brain stimulation target in individuals with Parkinson's disease. Despite evidence …
deep brain stimulation target in individuals with Parkinson's disease. Despite evidence …
[PDF][PDF] Organization of Purkinje cell development by neuronal MEGF11 in cerebellar granule cells
…, H Park, E Hwang, Y Yamamoto, K Tanaka-Yamamoto - Cell Reports, 2023 - cell.com
… Taegon Kim and members of the Tanaka-Yamamoto laboratory for valuable discussions,
and Dr. Helena Akiko Popiel for proofreading the manuscript. This work was supported by the …
and Dr. Helena Akiko Popiel for proofreading the manuscript. This work was supported by the …