User profiles for M. X. Zhu

Michael X. Zhu

Professor of Integrative Biology and Pharmacology, McGovern Medical School, The …
Verified email at uth.tmc.edu
Cited by 24876

The role of TRPMLs in endolysosomal trafficking and function

K Venkatachalam, CO Wong, MX Zhu - Cell calcium, 2015 - Elsevier
Members of the Transient Receptor Potential-Mucolipin (TRPML) constitute a family of
evolutionarily conserved cation channels that function predominantly in endolysosomal vesicles. …

Multiple roles of calmodulin and other Ca2+-binding proteins in the functional regulation of TRP channels

MX Zhu - Pflügers Archiv, 2005 - Springer
… Vaca and MX Zhu, unpublished results]. In these experiments, the intracellular Ca 2+ was
… Tang and MX Zhu, unpublished result). Functional studies will reveal whether one of them is …

TRPC channels: Structure, function, regulation and recent advances in small molecular probes

…, J Tian, Y Xiao, T Tian, F Xu, X Hong, MX Zhu - Pharmacology & …, 2020 - Elsevier
Transient receptor potential canonical (TRPC) channels constitute a group of receptor-operated
calcium-permeable nonselective cation channels of the TRP superfamily. The seven …

NAADP mobilizes calcium from acidic organelles through two-pore channels

…, J Parrington, J Ma, AM Evans, A Galione, MX Zhu - Nature, 2009 - nature.com
Ca 2+ mobilization from intracellular stores represents an important cell signalling process
1 that is regulated, in mammalian cells, by inositol-1,4,5-trisphosphate (InsP 3 ), cyclic ADP …

[PDF][PDF] A unified nomenclature for the superfamily of TRP cation channels

…, AM Scharenberg, G Schultz, N Shimizu, MX Zhu - Molecular cell, 2002 - cell.com
The TRP superfamily includes a diversity of non-voltagegated cation channels that vary
significantly in their selectivity and mode of activation. Nevertheless, members of the TRP …

[HTML][HTML] 2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3

…, LY Lee, JD Wood, MX Zhu - Journal of Biological …, 2004 - ASBMB
The transient receptor potential (TRP) superfamily contains a large number of proteins
encoding cation permeable channels that are further divided into TRPC (canonical), TRPM (…

[HTML][HTML] TPC proteins are phosphoinositide-activated sodium-selective ion channels in endosomes and lysosomes

…, A Goschka, D Shen, Y Zhou, J Harlow, MX Zhu… - Cell, 2012 - cell.com
Mammalian two-pore channel proteins (TPC1, TPC2; TPCN1, TPCN2) encode ion channels
in intracellular endosomes and lysosomes and were proposed to mediate endolysosomal …

Control of pollen tube tip growth by a Rop GTPase–dependent pathway that leads to tip-localized calcium influx

H Li, Y Lin, RM Heath, MX Zhu, Z Yang - The Plant Cell, 1999 - academic.oup.com
We have shown that Rop1At, a pollen-specific Rop GTPase that is a member of the Rho
family of small GTP binding proteins, acts as a key molecular switch controlling tip growth in …

Removal of an anionic dye by adsorption/precipitation processes using alkaline white mud

MX Zhu, L Lee, HH Wang, Z Wang - Journal of Hazardous Materials, 2007 - Elsevier
Alkaline white mud (AWM) has been investigated as a low-cost material for removal of an
anionic dye, acid blue 80. The effects of contact time, initial pH of dye solution, AWM dosage, …

Modulation of Ca2+ entry by polypeptides of the inositol 1,4,5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): Evidence for roles of TRP and IP3R in …

…, N Qin, M Jiang, A Dietrich, MX Zhu… - Proceedings of the …, 1999 - National Acad Sciences
Homologues of Drosophilia transient receptor potential (TRP) have been proposed to be
unitary subunits of plasma membrane ion channels that are activated as a consequence of …