[HTML][HTML] The suprachiasmatic nucleus: age-related decline in biological rhythms

TJ Nakamura, NN Takasu, W Nakamura - The journal of physiological …, 2016 - Springer
Aging is associated with changes in sleep duration and quality, as well as increased rates
of pathologic/disordered sleep. While several factors contribute to these changes, emerging …

Morning and evening physical exercise differentially regulate the autonomic nervous system during nocturnal sleep in humans

…, S Hashimoto, NN Takasu… - American Journal …, 2015 - journals.physiology.org
Effects of daily physical exercise in the morning or in the evening were examined on circadian
rhythms in plasma melatonin and core body temperature of healthy young males who …

Differential response of Period 1 expression within the suprachiasmatic nucleus

W Nakamura, S Yamazaki, NN Takasu… - Journal of …, 2005 - Soc Neuroscience
The suprachiasmatic nuclei (SCNs) of the hypothalamus contain a circadian clock that exerts
profound control over rhythmic physiology and behavior. The clock consists of multiple …

Repeated exposures to daytime bright light increase nocturnal melatonin rise and maintain circadian phase in young subjects under fixed sleep schedule

NN Takasu, S Hashimoto… - American Journal …, 2006 - journals.physiology.org
Effects of two different light intensities during daytime were examined on human circadian
rhythms in plasma melatonin, core body temperature, and wrist activity under a fixed sleep …

[PDF][PDF] Recovery from age-related infertility under environmental light-dark cycles adjusted to the intrinsic circadian period

NN Takasu, TJ Nakamura, IT Tokuda, T Todo… - Cell reports, 2015 - cell.com
Female reproductive function changes during aging with the estrous cycle becoming more
irregular during the transition to menopause. We found that intermittent shifts of the light-dark …

[HTML][HTML] Circadian regulation of food-anticipatory activity in molecular clock–deficient mice

NN Takasu, G Kurosawa, IT Tokuda, A Mochizuki… - PLoS …, 2012 - journals.plos.org
In the mammalian brain, the suprachiasmatic nucleus (SCN) of the anterior hypothalamus is
considered to be the principal circadian pacemaker, keeping the rhythm of most …

Dorsolateral prefrontal cortical oxygenation during REM sleep in humans

Y Kubota, NN Takasu, S Horita, M Kondo, M Shimizu… - Brain research, 2011 - Elsevier
Previous neuroimaging studies that examined cerebral blood flow during rapid eye movement
(REM) sleep have reported inconsistent findings regarding the activity of the dorsolateral …

[HTML][HTML] Importance of regular lifestyle with daytime bright light exposure on circadian rhythm sleep–wake disorders in pervasive developmental disorders

NN Takasu, M Toichi, W Nakamura - Japanese Dental Science Review, 2011 - Elsevier
Considerable attention has been paid to individuals showing social maladjustment as well
as withdrawal from social situations and activity, a state referred to as “Hikikomori” in …

Effects of regularizing sleep-wake schedules on daytime autonomic functions and psychological states in healthy university students with irregular sleep-wake habits

NN Takasu, Y Takenaka, M Fujiwara… - Sleep and Biological …, 2012 - Springer
The present study examined the effects of regularizing sleep-wake schedules on sleep,
autonomic function and mood/emotional and personality states in 14 habitually irregular sleepers…

[HTML][HTML] The central clock controls the daily rhythm of Aqp5 expression in salivary glands

H Uchida, TJ Nakamura, NN Takasu… - The journal of …, 2018 - Springer
Salivary secretion displays day–night variations that are controlled by the circadian clock.
The central clock in the suprachiasmatic nucleus (SCN) regulates daily physiological rhythms …