… Dittrich, PS & Manz, A. Single-molecule fluorescence detection in microfluidic channels
— … Dittrich, PS & Schwille, P. An integrated microfluidic system for reaction, high sensitivity …

The area of micro total analysis systems (μTAS), also called “lab on a chip”, miniaturized or
microfluidic analysis systems, is a rapidly developing field. During the last several years, we …

Multiplexed point-of-care testing (xPOCT), which is simultaneous on-site detection of different
analytes from a single specimen, has recently gained increasing importance for clinical …

… (94) To separate small molecules inside a droplet, Saucedo-Espinosa and Dittrich used
two carbon composite membranes to apply a uniform electric field across a microchannel to …

Fluorescence spectroscopic measurements at the single-molecule level usually require
large absorption cross sections and fluorescence quantum yields for the dyes under study. In …

Presented is a novel approach for an integrated micro total analysis system (μTAS) based
on a microfluidic on-chip device that supports ultrasensitive confocal detection of fluorescent …

Single cells represent the minimal functional unit of life. A major goal of biology is to understand
the mechanisms operating in this minimal unit. Nowadays, analysis of the single cell can …

Both single-molecule detection (SMD) methods and miniaturization technologies have
developed very rapidly over the last ten years. By merging these two techniques, it may be …

During the last century, an enormous number of protein functions were identified, many of
which can be generally described as catalytic. Ongoing research currently focuses on two …

Advances of analytical methods and emerging microfluidic tools have made it possible to
investigate biological processes in living organisms in detail and reach sensitivities sufficient …