NIDDK, JDRF, and the Diabetic Neuropathy Study Group of EASD sponsored a meeting to
explore the current status of animal models of diabetic peripheral neuropathy. The goal of the …

Diabetic neuropathy is a neurological complication of diabetes that causes significant
morbidity and, because of the obesity-driven rise in incidence of type 2 diabetes, is becoming a …

Diabetic neuropathy is a major complication of diabetes that affects the sensory and autonomic
nervous systems and leads to significant morbidity and impact on the quality of life of …

… The immunoblots were scanned and the data represented graphically as a ratio of
phosphorylated to total (p/t) protein. a) The graphs indicate the dose-dependent increase in p/t p38 …

In rodent models of diabetes, there are expression deficits in nerve growth factor (NGF) and
in mRNA for its high-affinity receptor, trkA, leading to decreased retrograde axonal transport …

… Where the F ratio gave P < 0.05, comparisons between individual group means were made
by Scheffe’s multiple range test at a significance level of P = 0.05. In all other situations, a …

Doxorubicin (DOX) is widely used for treating human cancers, but can induce heart failure
through an undefined mechanism. Herein we describe a previously unidentified signaling …

Mitochondrial dysfunction occurs in sensory neurons and may contribute to distal
axonopathy in animal models of diabetic neuropathy. The adenosine monophosphate-activated …

OBJECTIVE Impairments in mitochondrial function have been proposed to play a role in the
etiology of diabetic sensory neuropathy. We tested the hypothesis that mitochondrial …

… P < 0.05, comparisons between individual group means were made by Duncan's multiple
range test s at significance levels of P … Duncan's multiple range tests at P = 0.05 and P = 0.01: a …