User profiles for R. J. McLaughlin

Ryan McLaughlin

Associate Professor, Washington State University
Verified email at wsu.edu
Cited by 3894

A critical role for prefrontocortical endocannabinoid signaling in the regulation of stress and emotional behavior

RJ McLaughlin, MN Hill, BB Gorzalka - Neuroscience & Biobehavioral …, 2014 - Elsevier
The prefrontal cortex (PFC) provides executive control of the brain in humans and rodents,
coordinating cognitive, emotional, and behavioral responses to threatening stimuli and …

Cannabinoids and emotionality: a neuroanatomical perspective

RJ McLaughlin, G Gobbi - Neuroscience, 2012 - Elsevier
The endocannabinoid system has recently emerged as a promising therapeutic target for the
treatment of stress-related emotional disorders. A growing literature base has collectively …

Endogenous cannabinoid signaling is essential for stress adaptation

MN Hill, RJ McLaughlin, B Bingham… - Proceedings of the …, 2010 - National Acad Sciences
Secretion of glucocorticoid hormones during stress produces an array of physiological changes
that are adaptive and beneficial in the short term. In the face of repeated stress exposure…

Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response

MN Hill, RJ McLaughlin, B Pan… - Journal of …, 2011 - Soc Neuroscience
The mechanisms subserving the ability of glucocorticoid signaling within the medial
prefrontal cortex (mPFC) to terminate stress-induced activation of the hypothalamic–pituitary–…

The Detection of Large HNO3-Containing Particles in the Winter Arctic Stratosphere

…, MJ Northway, JC Holecek, SC Ciciora, RJ McLaughlin… - Science, 2001 - science.org
Large particles containing nitric acid (HNO 3 ) were observed in the 1999/2000 Arctic winter
stratosphere. These in situ observations were made over a large altitude range (16 to 21 …

[HTML][HTML] Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic–pituitary–adrenal axis

MN Hill, RJ McLaughlin, AC Morrish, V Viau… - …, 2009 - nature.com
RJ McLaughlin, BB Gorzalka and CJ Hillard, unpublished findings). Furthermore, despite
the fact that tissue measurements of FAAH activity and AEA content were performed in sections …

[HTML][HTML] Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain

D De Gregorio, RJ McLaughlin, L Posa… - Pain, 2019 - journals.lww.com
… De Gregorio, Danilo a ; McLaughlin, Ryan J. b ; Posa, Luca a,c ; Ochoa-Sanchez, Rafael a
; Enns, Justine a ; Lopez-… De Gregorio and RJ McLaughlin contributed equally to this work. …

[PDF][PDF] An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates

…, D Panovska, F De Smet, FJT Staal, RJ Mclaughlin… - Cancer cell, 2020 - cell.com
Heterogeneity of lung tumor endothelial cell (TEC) phenotypes across patients, species (human/mouse),
and models (in vivo/in vitro) remains poorly inventoried at the single-cell level. …

[PDF][PDF] Single-cell RNA sequencing maps endothelial metabolic plasticity in pathological angiogenesis

…, D Panovska, F De Smet, FJT Staal, RJ Mclaughlin… - Cell metabolism, 2020 - cell.com
Endothelial cell (EC) metabolism is an emerging target for anti-angiogenic therapy in tumor
angiogenesis and choroidal neovascularization (CNV), but little is known about individual …

Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment

MN Hill, EJ Carrier, RJ McLaughlin… - Journal of …, 2008 - Wiley Online Library
It has been suggested that disturbances in endocannabinoid signaling contribute to the
development of depressive illness; however, at present there is insufficient evidence to allow for …