User profiles for R. M. Reilly

Raymond Reilly

Professor and Director, Centre for Pharmaceutical Oncology, Leslie Dan Faculty of …
Verified email at utoronto.ca
Cited by 9717

Semantic representation and naming in children with specific language impairment

KK McGregor, RM Newman, RM Reilly, NC Capone - 2002 - ASHA
When 16 children with SLI (mean age= 6; 2) and 16 normally developing age-mates named
age-appropriate objects, the SLI cohort made more naming errors. For both cohorts, …

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice

…, L Frost, PE Kroeger, RM Reilly… - Proceedings of the …, 2002 - National Acad Sciences
The role of protein-tyrosine phosphatase 1B (PTP1B) in diabetes was investigated using an
antisense oligonucleotide in ob/ob and db/db mice. PTP1B antisense oligonucleotide …

The effects of particle size and molecular targeting on the intratumoral and subcellular distribution of polymeric nanoparticles

H Lee, H Fonge, B Hoang, RM Reilly… - Molecular …, 2010 - ACS Publications
The current study describes the impact of particle size and/or molecular targeting (epidermal
growth factor, EGF) on the in vivo transport of block copolymer micelles (BCMs) in athymic …

Semantic representation and naming in young children

KK McGregor, RM Friedman, RM Reilly, RM Newman - 2002 - ASHA
Children's semantic representations and semantic naming errors were the focus of this study.
In Experiment 1, 25 normally developing children (mean age= 5 years 4 months) named, …

Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation

…, KL Chu, CR Faltynek, ME Kort, RM Reilly… - Pain, 2011 - journals.lww.com
Despite the increasing interest in TRPA1 channel as a pain target, its role in cold sensation
and body temperature regulation is not clear; the efficacy and particularly side effects …

Endothelial apoptosis initiates acute blood–brain barrier disruption after ionizing radiation

YQ Li, P Chen, A Haimovitz-Friedman, RM Reilly… - Cancer research, 2003 - AACR
Acute disruption of blood–brain barrier (BBB) is well recognized after radiation therapy to the
central nervous system (CNS). We assessed the genetic regulation of acute BBB disruption …

[HTML][HTML] Auger electrons for cancer therapy–a review

A Ku, VJ Facca, Z Cai, RM Reilly - EJNMMI radiopharmacy and chemistry, 2019 - Springer
Background Auger electrons (AEs) are very low energy electrons that are emitted by
radionuclides that decay by electron capture (eg 111 In, 67 Ga, 99m Tc, 195m Pt, 125 I and 123 I). …

MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases

Y Meng, RM Reilly, RC Pezo, M Trudeau… - Science translational …, 2021 - science.org
The blood-brain barrier (BBB) is an important factor limiting the effectiveness of central nervous
system (CNS) therapeutics. MR-guided focused ultrasound (MRgFUS) is a noninvasive, …

Carbon nanotubes: potential benefits and risks of nanotechnology in nuclear medicine

RM Reilly - Journal of Nuclear Medicine, 2007 - Soc Nuclear Med
Targeting of tumors with radionuclides for radiotherapeutic purposes is often limited by
inadequate delivery to lesions using currently available targeting vehicles (eg, monoclonal …

T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC

D Haasch, YW Chen, RM Reilly, XG Chiou… - Cellular …, 2002 - Elsevier
In a search for novel early T cell activation transcripts, we identified expressed sequence tags
(ESTs) more abundantly expressed in normal human CD4 + T lymphocytes fully activated …