User profiles for R. Balice-Gordon

Rita Balice-Gordon

CEO, Muna Therapeutics, Adjunct Professor of Neuroscience, Univ. of Pennsylvania Sch of …
Verified email at munatherapeutics.com
Cited by 24343

Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies

…, SK Dessain, MR Rosenfeld, R Balice-Gordon… - The Lancet …, 2008 - thelancet.com
Background A severe form of encephalitis associated with antibodies against NR1–NR2
heteromers of the NMDA receptor was recently identified. We aimed to analyse the clinical and …

Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study

…, A Saiz, MR Rosenfeld, R Balice-Gordon… - The Lancet …, 2013 - thelancet.com
Background Anti-NMDA receptor (NMDAR) encephalitis is an autoimmune disorder in which
the use of immunotherapy and the long-term outcome have not been defined. We aimed to …

Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis

…, MR Rosenfeld, R Balice-Gordon - The Lancet …, 2011 - thelancet.com
Since its discovery in 2007, the encephalitis associated with antibodies against the N-methyl-D-aspartate
receptor (NMDAR) has entered the mainstream of neurology and other …

Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis

…, DR Lynch, J Dalmau, RJ Balice-Gordon - Journal of …, 2010 - Soc Neuroscience
We recently described a severe, potentially lethal, but treatment-responsive encephalitis that
associates with autoantibodies to the NMDA receptor (NMDAR) and results in behavioral …

AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location

…, F Graus, DR Lynch, R BaliceGordon… - Annals of …, 2009 - Wiley Online Library
Objective To report the clinical and immunological features of a novel autoantigen related to
limbic encephalitis (LE) and the effect of patients' antibodies on neuronal cultures. Methods …

Antibodies to the GABAB receptor in limbic encephalitis with seizures: case series and characterisation of the antigen

…, F Graus, SJ Moss, R Balice-Gordon… - The Lancet …, 2010 - thelancet.com
Background Some encephalitides or seizure disorders once thought idiopathic now seem to
be immune mediated. We aimed to describe the clinical features of one such disorder and …

Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study

…, F Leypoldt, AJ Gleichman, R Balice-Gordon… - The Lancet …, 2014 - thelancet.com
Background Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a severe but treatable
autoimmune disorder which diagnosis depends on sensitive and specific antibody testing. …

Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series

…, F Graus, L Bataller, R Balice-Gordon… - The Lancet …, 2010 - thelancet.com
Background Voltage-gated potassium channels are thought to be the target of antibodies
associated with limbic encephalitis. However, antibody testing using cells expressing voltage-…

Encephalitis with refractory seizures, status epilepticus, and antibodies to the GABAA receptor: a case series, characterisation of the antigen, and analysis of the …

…, P Sillevis-Smitt, MJ Titulaer, R Balice-Gordon… - The lancet …, 2014 - thelancet.com
Background Increasing evidence suggests that seizures and status epilepticus can be
immune-mediated. We aimed to describe the clinical features of a new epileptic disorder, and to …

Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

…, MJ Titulaer, M Petit-Pedrol, A Jain, R Balice-Gordon… - Brain, 2015 - academic.oup.com
Anti-N-methyl D-aspartate receptor (NMDAR) encephalitis is a severe neuropsychiatric
disorder that associates with prominent memory and behavioural deficits. Patients’ antibodies …