User profiles for R. Raghupathi

Ramesh Raghupathi

Professor of Neurobiology and Anatomy, Drexel University
Verified email at drexel.edu
Cited by 12945

Cell death mechanisms following traumatic brain injury

R Raghupathi - Brain pathology, 2004 - Wiley Online Library
Neuronal and glial cell death and traumatic axonal injury contribute to the overall pathology
of traumatic brain injury (TBI) in both humans and animals. In both head‐injured humans …

Apoptosis after traumatic brain injury

R Raghupathi, DI Graham, TK McINTOSH - Journal of neurotrauma, 2000 - liebertpub.com
Apoptosis of neurons and glia contribute to the overall pathology of traumatic brain injury (TBI)
in both humans and animals. In both head-injured humans and following experimental …

Calpain as a therapeutic target in traumatic brain injury

KE Saatman, J Creed, R Raghupathi - Neurotherapeutics, 2010 - Springer
… Huh JW, Franklin MA, Widing AG, Raghupathi R. Regionally distinct patterns of calpain …
Raghupathi R. Cell death mechanisms following traumatic brain injury. Brain Pathol 2004;14…

Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period

AC Conti, R Raghupathi, JQ Trojanowski… - Journal of …, 1998 - Soc Neuroscience
The temporal pattern of apoptosis in the adult rat brain after lateral fluid-percussion (FP)
brain injury was characterized using terminal deoxynucleotidyl-transferase-mediated biotin-…

Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury

U Scherbel, R Raghupathi… - Proceedings of the …, 1999 - National Acad Sciences
The present study evaluated behavioral and histopathological outcome after controlled cortical
impact (CCI) brain injury in mice deficient in tumor necrosis factor [TNF(−/−)] and their wild…

Mild head injury increasing the brain's vulnerability to a second concussive impact

…, L Longhi, R Hoover, KE Saatman, R Raghupathi… - Journal of …, 2001 - thejns.org
Object. Mild, traumatic repetitive head injury (RHI) leads to neurobehavioral impairment and
is associated with the early onset of neurodegenerative disease. The authors developed an …

Temporal window of vulnerability to repetitive experimental concussive brain injury

L Longhi, KE Saatman, S Fujimoto, R Raghupathi… - …, 2005 - journals.lww.com
OBJECTIVE: Repetitive concussive brain injury (CBI) is associated with cognitive alterations
and increased risk of neurodegenerative disease. METHODS: To evaluate the temporal …

Transplanted neural stem cells survive, differentiate, and improve neurological motor function after experimental traumatic brain injury

…, HL Laurer, LG Longhi, R Raghupathi… - …, 2002 - journals.lww.com
OBJECTIVE: Using the neural stem cell (NSC) clone C17. 2, we evaluated the ability of
transplanted murine NSCs to attenuate cognitive and neurological motor deficits after traumatic …

Age-dependent changes in material properties of the brain and braincase of the rat

A Gefen, N Gefen, Q Zhu, R Raghupathi… - Journal of …, 2003 - liebertpub.com
Clinical and biomechanical evidence indicates that mechanisms and pathology of head
injury in infants and young children may be different from those in adults. Biomechanical …

Structural and functional damage sustained by mitochondria after traumatic brain injury in the rat: evidence for differentially sensitive populations in the cortex and …

…, RW Neumar, R Raghupathi… - Journal of Cerebral …, 2003 - journals.sagepub.com
The cellular and molecular pathways initiated by traumatic brain injury (TBI) may compromise
the function and structural integrity of mitochondria, thereby contributing to cerebral …