User profiles for S. E. Hammack

Sayamwong E. Hammack

Professor of Psychological Science, University of Vermont
Verified email at uvm.edu
Cited by 5722

Overlapping neurobiology of learned helplessness and conditioned defeat: implications for PTSD and mood disorders

SE Hammack, MA Cooper, KR Lezak - Neuropharmacology, 2012 - Elsevier
Exposure to traumatic events can increase the risk for major depressive disorder (MDD) as
well as posttraumatic stress disorder (PTSD), and pharmacological treatments for these …

Roles for pituitary adenylate cyclase-activating peptide (PACAP) expression and signaling in the bed nucleus of the stria terminalis (BNST) in mediating the behavioral …

SE Hammack, CW Roman, KR Lezak… - Journal of molecular …, 2010 - Springer
Anxiety disorders are frequently long-lasting and debilitating for more than 40 million American
adults. Although stressor exposure plays an important role in the etiology of some anxiety …

Pituitary adenylate cyclase activating polypeptide in stress-related disorders: data convergence from animal and human studies

SE Hammack, V May - Biological psychiatry, 2015 - Elsevier
… , we were unable to produce the same increase in PACAP transcript (55), nor did we observe
these increases following repeated treatment with a ghrelin agonist (Lezak and Hammack, …

Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor

…, AJ Myers, M Ramirez, A Engel, SE Hammack… - Nature, 2011 - nature.com
Pituitary adenylate cyclase-activating polypeptide (PACAP) is known to broadly regulate the
cellular stress response. In contrast, it is unclear if the PACAP–PAC1 receptor pathway has …

Activation of serotonin-immunoreactive cells in the dorsal raphe nucleus in rats exposed to an uncontrollable stressor

RE Grahn, MJ Will, SE Hammack, S Maswood… - Brain research, 1999 - Elsevier
The dorsal raphe nucleus (DRN) and its serotonergic terminal regions have been suggested
to be part of the neural substrate by which exposure to uncontrollable stressors produces …

Chronic stress increases pituitary adenylate cyclase-activating peptide (PACAP) and brain-derived neurotrophic factor (BDNF) mRNA expression in the bed nucleus of …

SE Hammack, J Cheung, KM Rhodes… - …, 2009 - Elsevier
Exposure to chronic stress has been argued to produce maladaptive anxiety-like behavioral
states, and many of the brain regions associated with stressor responding also mediate …

Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10

…, L Spataro, J Wieseler-Frank, SE Hammack… - Molecular …, 2005 - journals.sagepub.com
Despite many decades of drug development, effective therapies for neuropathic pain remain
elusive. The recent recognition of spinal cord glia and glial pro-inflammatory cytokines as …

Differential expression of 5HT‐1A, α1b adrenergic, CRF‐R1, and CRF‐R2 receptor mRNA in serotonergic, γ‐aminobutyric acidergic, and catecholaminergic cells of …

…, BN Greenwood, SE Hammack… - Journal of …, 2004 - Wiley Online Library
The dorsal raphe nucleus (DR) has a topographic neuroanatomy consistent with the idea
that different parts of this nucleus subserve different functions. Here we use dual in situ …

Corticotropin releasing hormone type 2 receptors in the dorsal raphe nucleus mediate the behavioral consequences of uncontrollable stress

SE Hammack, MJ Schmid, ML LoPresti… - Journal of …, 2003 - Soc Neuroscience
Uncontrollable shock produces a constellation of behavioral changes that are not observed
after equivalent escapable shock. These include interference with escape and potentiation …

The role of corticotropin-releasing hormone in the dorsal raphe nucleus in mediating the behavioral consequences of uncontrollable stress

SE Hammack, KJ Richey, MJ Schmid… - Journal of …, 2002 - Soc Neuroscience
Inescapable shock (IS) produces subsequent interference with escape behavior and increased
fear conditioning that has been linked to increased activity and release of serotonin (5-HT…