Although hippocampal interneurons typically do not show discrete regions of elevated firing
in an environment, such as seen in pyramidal cell place fields, they do exhibit significant …

The factors that control the spatial tuning of hippocampal neurons are incompletely understood,
and there is no generally agreed upon definition of what constitutes a “place field”. One …

… These results were refined manually with custom-written software (MClust, author: AD
Redish, University of Minnesota; Waveform Cutter, author: SL Cowen). No attempt was made to …

The medial prefrontal cortex (mPFC) plays a critical role in the organization of goal-directed
behaviors and in the learning of reinforcement contingencies. Given these observations, it …

Biofouling is a prevalent issue in studies that involve prolonged implantation of electrochemical
probes in the brain. In long-term fast-scan cyclic voltammetry (FSCV) studies, biofouling …

Objective— Long noncoding RNAs (lncRNAs) represent a rapidly growing class of RNA
genes with functions related primarily to transcriptional and post-transcriptional control of gene …

Spatial and episodic memory performance declines with age, and the neural basis for this
decline is not well understood. Sharp-wave ripples are brief (∼70 ms) high-frequency …

Sleep is recognized as a physiological state associated with learning, with studies showing
that knowledge acquisition improves with naps. Little work has examined sleep-dependent …

Cognitive flexibility, the ability to adapt behavior to changing outcomes, is critical to survival.
The prefrontal cortex is a key site of cognitive control, and chronic pain is known to lead to …

… We are give special thanks to Paulluvi Bahl, Benjamin Davis, Katherine Gies, Colin Kyle,
Giulia Seghezzo, Maddie Otto, and collectively the undergraduates of the Cowen and Falk-…