… The function of SET-domain proteins is to transfer a methyl group from S-adenosyl-L-methionine
(AdoMet) to the amino group of a lysine residue on the histone or other protein, leaving a …

Emerging models of the bacterial nucleoid show that nucleoid-associated proteins (NAPs)
and transcription contribute in combination to the dynamic nature of nucleoid structure. NAPs …

Since their discovery in 1998, the two TNF family members APRIL and BLyS/BAFF have
received increasing attention. In addition to regulating normal B-cell development and immune …

We report the generation and analysis of functional data from multiple, diverse experiments
performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE …

Background Transplantation of human embryonic dopamine neurons into the brains of patients
with Parkinson's disease has proved beneficial in open clinical trials. However, whether …

Cytokines are important in the regulation of haematopoiesis and immune responses, and can
influence lymphocyte development. Here we have identified a class I cytokine receptor that …

… Brownstein 39 , Kevin Bundy 40 , Martin Bureau 41 , Adam Burgasser 42 , Etienne Burtin 11 ,
Mariana Cano-Díaz 15 , Raffaella Capasso 43,44,45 , Michele Cappellari 41 , Ricardo Carrera …

… Each ink exhibits highly shear thinning behavior with respective apparent viscosities ranging
from 10 3–10 4 Pa · s at 1 s −1. Figure 2 c shows their storage modulus ( G’) as a function of …

B cells are important in the development of autoimmune disorders by mechanisms involving
disregulated polyclonal B-cell activation, production of pathogenic antibodies, and co-…

T cell–derived cytokines are important in the development of an effective immune response,
but when dysregulated they can promote disease. Here we identify a four-helix bundle …