… For example, nitric oxide, a short-lived (t 1/2 = up to 30 s) highly diffusible free radical
generated from L-arginine (56), acts as a second messenger to regulate a variety of physiological …

A SERIES of genomic and complementary DNA clones encoding new putative members of
G protein-coupled receptors were isolated using homology cloning and low-stringency …

Phosphotidylinositol (PtdIns) signaling is tightly regulated both spatially and temporally by
subcellularly localized PtdIns kinases and phosphatases that dynamically alter downstream …

Insulin is the primary hormone involved in glucose homeostasis, and impairment of insulin
action and/or secretion has a critical role in the pathogenesis of diabetes mellitus. Type-II SH2…

… The percentage of cells in the G0/G1, S and G2/M phases of the cycle are indicated. Results
… P < 0.04), and the number of cells in S or G2/M phases was significantly increased in Inpp5e …

The aging process is driven by interrelated mechanisms that lead to the emergence of
characteristic phenotypes that include changes in body composition, energy production and …

… PI4P antibody was used according to the manufacturer’s instructions. For Tulp3 staining,
cells were fixed for 10 min at 4 C in acetone. After fixation, cells were blocked in PBS containing …

… mice was dissected in Hank’s medium (HBBS 13 without Ca2+ and Mg2+) and digested for
1 hr with 0.25% trypsin and 0.01% DNase in Earle’s balanced salt solution (EBSS 13 Ca2+ …

The aging process is driven by a finite number of inter‐related mechanisms that ultimately
lead to the emergence of characteristic phenotypes, including increased susceptibility to …

… Locomotion was analyzed during two successive periods of 60 s by using the optoelectronic
… a similar level of alertness, a short air puff was given on the back part of animal every 5 s. …