[HTML][HTML] Vestibular deficits in deafness: Clinical presentation, animal modeling, and treatment solutions

A Maudoux, S Vitry, A El-Amraoui - Frontiers in neurology, 2022 - frontiersin.org
… However, WHRN-S expression is sufficient to maintain stereociliary bundle morphology
and function in a subset of hair cells, resulting in some auditory responses, but no overt …

A role for CXCR4 signaling in survival and migration of neural and oligodendrocyte precursors

M Dziembowska, TN Tham, P Lau, S Vitry, F Lazarini… - Glia, 2005 - Wiley Online Library
Oligodendrocyte development is controlled by a number of survival and migratory factors.
The present study shows that signaling of CXCR4 receptor by the chemokine CXCL12 …

[HTML][HTML] Early neurodegeneration progresses independently of microglial activation by heparan sulfate in the brain of mucopolysaccharidosis IIIB mice

…, N Desmaris, S Bigou, R Attali, S Corbineau, S Vitry… - PLoS …, 2008 - journals.plos.org
S. Akira and Dr. M. … We are grateful to S. Blanchard for excellent technical help and to H.
Fsiho for … Masuda H, Shichijo S (1981) Isolation and characterization of glycosaminoglycans …

Modeling neuronal defects associated with a lysosomal disorder using patient-derived induced pluripotent stem cells

…, S Bigou, R Froissart, I Rouvet, S Vitry… - Human molecular …, 2011 - academic.oup.com
By providing access to affected neurons, human induced pluripotent stem cells (iPSc) offer
a unique opportunity to model human neurodegenerative diseases. We generated human …

Inhibition of polyamine biosynthesis is a broad-spectrum strategy against RNA viruses

…, E Simon-Loriere, M Prot, C Tamietti, S Vitry… - Journal of …, 2016 - Am Soc Microbiol
RNA viruses present an extraordinary threat to human health, given their sudden and
unpredictable appearance, the potential for rapid spread among the human population, and their …

Migration and multipotentiality of PSA-NCAM+ neural precursors transplanted in the developing brain

S Vitry, V Avellana-Adalid, F Lachapelle… - Molecular and Cellular …, 2001 - Elsevier
… (around 9 ml per gradient), washed with Hank’s medium, and centrifuged 10 min at 2500 tpm…
After 60 min, floating cells, depleted of adhering astrocytes, were washed with Hank’s, centri…

[HTML][HTML] Storage vesicles in neurons are related to Golgi complex alterations in mucopolysaccharidosis IIIB

S Vitry, J Bruyère, M Hocquemiller, S Bigou… - The American journal of …, 2010 - Elsevier
… Author links open overlay panel Sandrine Vitry * † , Julie Bruyère * † , Michaël Hocquemiller
* … Ultrathin sections (70 nm) were prepared using a Reichert Ultracut S Wild M3z microtome (…

Heparan sulfate saccharides modify focal adhesions: implication in mucopolysaccharidosis neuropathophysiology

…, H Lortat-Jacob, JM Heard, S Vitry - Journal of molecular …, 2015 - Elsevier
… We measured Cdc42-GTP amounts in astrocytes immediately or 30 min after wound by
pulling down Cdc42 bound to PAK using GST (glutathione S-transferase)-PAK. Cdc42-GTP and …

Migrating and myelinating potential of neural precursors engineered to overexpress PSA-NCAM

I Franceschini, S Vitry, F Padilla, P Casanova… - Molecular and Cellular …, 2004 - Elsevier
Polysialic acid (PSA) on NCAM is an important modulator of cell–cell interactions during
development and regeneration. Here we investigated whether PSA overexpression influences …

Enhanced degradation of synaptophysin by the proteasome in mucopolysaccharidosis type IIIB

S Vitry, J Ausseil, M Hocquemiller, S Bigou… - Molecular and Cellular …, 2009 - Elsevier
The interruption of the lysosomal degradation of heparan sulfate oligosaccharides has
deleterious consequences on the central nervous system in children or in animals with …