In general, iron represents a double-edged sword in metabolism in most tissues, especially
in the brain. Although the high metabolic demands of brain cells require iron as a redox-…

Background and Purpose— Stroke diagnosis could be challenging in the acute phase. We
aimed to develop a blood-based diagnostic tool to differentiate between real strokes and …

This study was designed to assess the potential neuroprotective effect of several imidazol(ine)
drugs and agmatine on glutamate‐induced necrosis and on apoptosis induced by low …

… Statistical significance of differences was determined using Student t test or 1-way ANOVA
… Correspondence to Teresa Gasull, Neuroscience Basic Research Lab, Fundació Institut d’…

Despite transferrin being the main circulating carrier of iron in body fluids, and iron overload
conditions being known to worsen stroke outcome through reactive oxygen species (ROS)-…

In the search of animal stroke models providing translational advantages for biomedical
research, pigs are large mammals with interesting brain characteristics and wide social …

A role of iron as a target to prevent stroke-induced neurodegeneration has been recently
revisited due to new evidence showing that ferroptosis inhibitors are protective in experimental …

Objective Blood biomarkers have not been widely investigated in poststroke epilepsy. In this
study, we aimed to describe clinical factors and biomarkers present during acute stroke and …

For the first time, a paper-based analytical device (PAD) was developed for the assessment
of transferrin saturation (TSAT), which is defined as the ratio between iron bound to …

Mature cerebellar granule cells in culture die by a process that requires new RNA and protein
synthesis when deprived of depolarizing concentrations of potassium. We investigated …