Copy number variation at 22q11. 2: from rare variants to common mechanisms of developmental neuropsychiatric disorders

…, A Hishimoto, T Izumi, S Boku, T Hiramoto - Molecular …, 2013 - nature.com
Recently discovered genome-wide rare copy number variants (CNVs) have unprecedented
levels of statistical association with many developmental neuropsychiatric disorders, …

Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice

Y Asano, T Hiramoto, R Nishino… - American Journal …, 2012 - journals.physiology.org
There is increasing interest in the bidirectional communication between the mammalian host
and prokaryotic cells. Catecholamines (CA), candidate molecules for such communication, …

Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer

T Hiramoto, T Nakanishi, T Sumiyoshi, T Fukuda… - Oncogene, 1999 - nature.com
Association of breast tumor susceptibility gene products BRCA1 and BRCA2 with the RAD51
recombination protein suggested that cancer could arise through defects in recombination. …

Hydrogenases from Methanogenic Archaea, Nickel, a Novel Cofactor, and H2 Storage

…, M Goenrich, M Schick, T Hiromoto… - Annual review of …, 2010 - annualreviews.org
Most methanogenic archaea reduce CO 2 with H 2 to CH 4 . For the activation of H 2 , they
use different [NiFe]-hydrogenases, namely energy-converting [NiFe]-hydrogenases, …

Commensal microbiota modulate murine behaviors in a strictly contamination‐free environment confirmed by culture‐based methods

…, S Tomonaga, M Furuse, T Hiramoto… - …, 2013 - Wiley Online Library
Background There is increasing evidence suggesting the existence of an interaction between
commensal microbiota, the gut and the brain. The aim of this study was to examine the …

Effects of traps on charge storage characteristics in metal-oxide-semiconductor memory structures based on silicon nanocrystals

Y Shi, K Saito, H Ishikuro, T Hiramoto - Journal of Applied Physics, 1998 - pubs.aip.org
Charge storage characteristics have been investigated in metal-oxide-semiconductor memory
structures based on silicon nanocrystals, where various interface traps and defects were …

Extracellular signal-regulated kinase 2 (ERK2) knockdown mice show deficits in long-term memory; ERK2 has a specific function in learning and memory

…, K Yamada, M Ito, M Kuroki, T Hiramoto… - Journal of …, 2007 - Soc Neuroscience
The extracellular signal-regulated kinase (ERK) 1 and 2 are important signaling components
implicated in learning and memory. These isoforms display a high degree of sequence …

Understanding random threshold voltage fluctuation by comparing multiple fabs and technologies

…, A Nishida, S Kamohara, T Hiramoto - 2007 IEEE …, 2007 - ieeexplore.ieee.org
Random threshold voltage (V M ) fluctuation data obtained from multiple fabs, generations
and technologies, as well as theoretical / TCAD results are carefully compared using a special …

ERK2 contributes to the control of social behaviors in mice

…, T Ikeda, A Takeuchi, T Hiramoto… - Journal of …, 2011 - Soc Neuroscience
Signaling through extracellular signal-regulated kinase (ERK) is important in multiple signal
transduction networks in the CNS. However, the specific role of ERK2 in in vivo brain …

Quantum mechanical effects in the silicon quantum dot in a single-electron transistor

H Ishikuro, T Hiramoto - Applied Physics Letters, 1997 - pubs.aip.org
The quantum mechanical effects in silicon single-electron transistors have been investigated.
The devices have been fabricated in the form of point contact metal–oxide–semiconductor …