Production of tumor necrosis factor-alpha by microglia and astrocytes in culture

M Sawada, N Kondo, A Suzumura, T Marunouchi - Brain research, 1989 - Elsevier
… Microglia produced significantly higher TNF activity than astrocytes in response to graded
concentration of LPS (P < 0.001 by t-test). Microglia produced 1.9 U/105 cells of cytotoxicity by …

Transforming growth factor-beta suppresses activation and proliferation of microglia in vitro.

…, M Sawada, H Yamamoto, T Marunouchi - Journal of immunology …, 1993 - journals.aai.org
… TGF-/3 is a 24-kDa protein produced by various types of cells, including T and B lymphocytes
and … , and differentiation of T cells and production of cytokine by T cells (19, 26, 28). As well, …

Interleukin‐10 inhibits both production of cytokines and expression of cytokine receptors in microglia

…, H Hosoya, T Marunouchi, T Nagatsu - Journal of …, 1999 - Wiley Online Library
… Mouse and human IL-10 inhibit cytokine synthesis by activated T cells, natural killer cells,
and monocyte/macrophage. Like other cytokines, IL-10 has a wide range of functions; it inhibits …

Isolation of multipotent stem cells from mouse adipose tissue

…, S Nakata, M Ohkuma, EI Miyachi, T Marunouchi… - Journal of …, 2007 - Elsevier
… Data are presented as the mean value ± SD Differences between two groups were evaluated
for statistical significance using Student's t-test. Differences were considered significant at …

CDH1 is a specific marker for undifferentiated spermatogonia in mouse testes

…, Y Kadokawa, H Kurahashi, T Marunouchi - Biology of …, 2007 - academic.oup.com
In the mammalian testis, spermatogenesis is initiated from a subset of stem cells belonging
to undifferentiated type A spermatogonia. In spite of the biologic significance of …

Increased water intake decreases progression of polycystic kidney disease in the PCK rat

…, H Kurahashi, T Marunouchi… - Journal of the …, 2006 - journals.lww.com
… Membranes then were washed three times with TBS-T and incubated with secondary … in
TBS-T for 1 h at room temperature. The membranes were washed three times with TBS-T, and …

Cell death in the cardiac myocyte

T Marunouchi, K Tanonaka - Biological and Pharmaceutical Bulletin, 2015 - jstage.jst.go.jp
Loss of cardiac myocytes plays a critical role in the pathogenesis of cardiovascular disorders.
A decrease in the number of cardiac myocytes in cardiac diseases results in sustained, …

Expression of cytokine receptors in cultured neuronal and glial cells

M Sawada, Y Itoh, A Suzumura, T Marunouchi - Neuroscience letters, 1993 - Elsevier
… and Marunouchi, T., Production of interleukin-5 by mouse astrocytes and microglia in culture,
… and Marunouchi, T.. Effects of colony stimulating t~.ctors on isolated microglia in vitro. J. …

Production of interleukin-10 by mouse glial cells in culture

T Mizuno, M Sawada, T Marunouchi… - … and biophysical research …, 1994 - Elsevier
… enccphalomyelitis (EAE) produced by the transfer of myelin basic protein-specific T cell … It
is produced by a variety of cell types, including type 2 helper T cells(Th2), B cells, macrophages…

Activation and proliferation of the isolated microglia by colony stimulating factor-1 and possible involvement of protein kinase C

M Sawada, A Suzumura, H Yamamoto, T Marunouchi - Brain research, 1990 - Elsevier
… and Marunouchi, T., Macrophage-like properties of isolated mouse microglia cells, Neurochem.
Res., 13 (1988) 1082. 29 Schelper, RL and Adrian, EK, Non-specific esterase activity in …