User profiles for V. Senatorov
Vlad SenatorovReservoir Neuroscience Verified email at reservoirneuro.com Cited by 1370 |
Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases
…, C Hough, VV Senatorov - Annu. Rev. Pharmacol …, 2005 - annualreviews.org
▪ Abstract Increasing evidence supports the notion that glyceraldehyde-3-phosphate
dehydrogenase (GAPDH) is a protein with multiple functions, including its surprising role in …
dehydrogenase (GAPDH) is a protein with multiple functions, including its surprising role in …
Neuroprotective effects of lithium in cultured cells and animal models of diseases
…, M Ren, R Hashimoto, V Senatorov… - Bipolar …, 2002 - Wiley Online Library
Lithium, the major drug used to treat manic depressive illness, robustly protects cultured rat
brain neurons from glutamate excitotoxicity mediated by N‐methyl‐D‐aspartate (NMDA) …
brain neurons from glutamate excitotoxicity mediated by N‐methyl‐D‐aspartate (NMDA) …
Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model
…, M Ericsson, KD Onos, R Veksler, VV Senatorov Jr… - Brain, 2018 - academic.oup.com
The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic
encephalopathy, and the relationships between these disorders, are poorly understood. We …
encephalopathy, and the relationships between these disorders, are poorly understood. We …
Control of extracellular cleavage of ProBDNF by high frequency neuronal activity
…, E Zaitsev, VV Senatorov Jr… - Proceedings of the …, 2009 - National Acad Sciences
Pro- and mature neurotrophins often elicit opposing biological effects. For example, mature
brain-derived neurotrophic factor (mBDNF) is critical for long-term potentiation induced by …
brain-derived neurotrophic factor (mBDNF) is critical for long-term potentiation induced by …
The role of free-fatty acid receptor-4 (FFA4) in human cancers and cancer cell lines
IS Senatorov, NH Moniri - Biochemical pharmacology, 2018 - Elsevier
A dietary influence on cancer progression has been evident for many decades, and dietary
fatty acids, particularly long chain mono- and polyunsaturated fatty acids, have been shown …
fatty acids, particularly long chain mono- and polyunsaturated fatty acids, have been shown …
Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model
M Ren, VV Senatorov, RW Chen… - Proceedings of the …, 2003 - National Acad Sciences
Lithium has long been a primary drug used to treat bipolar mood disorder, even though the
drug's therapeutic mechanisms remain obscure. Recent studies demonstrate that lithium has …
drug's therapeutic mechanisms remain obscure. Recent studies demonstrate that lithium has …
Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction
VV Senatorov Jr, AR Friedman, DZ Milikovsky… - Science Translational …, 2019 - science.org
Aging involves a decline in neural function that contributes to cognitive impairment and
disease. However, the mechanisms underlying the transition from a young-and-healthy to aged-…
disease. However, the mechanisms underlying the transition from a young-and-healthy to aged-…
Expression of mutated mouse myocilin induces open-angle glaucoma in transgenic mice
V Senatorov, I Malyukova, R Fariss… - Journal of …, 2006 - Soc Neuroscience
We developed a genetic mouse model of open-angle glaucoma by expression of mutated
mouse myocilin (Myoc) in transgenic (Tg) mice. The Tyr423His point mutation, corresponding …
mouse myocilin (Myoc) in transgenic (Tg) mice. The Tyr423His point mutation, corresponding …
CATH: expanding the horizons of structure-based functional annotations for genome sequences
…, A Tolulope, HM Scholes, I Senatorov… - Nucleic acids …, 2019 - academic.oup.com
This article provides an update of the latest data and developments within the CATH protein
structure classification database ( http://www.cathdb.info ). The resource provides two levels …
structure classification database ( http://www.cathdb.info ). The resource provides two levels …
Imaging blood–brain barrier dysfunction as a biomarker for epileptogenesis
…, I Noyman, R Veksler, H Dalipaj, VV Senatorov Jr… - Brain, 2017 - academic.oup.com
A biomarker that will enable the identification of patients at high-risk for developing post-injury
epilepsy is critically required. Microvascular pathology and related blood–brain barrier …
epilepsy is critically required. Microvascular pathology and related blood–brain barrier …