Antihistamine use in children

R Fitzsimons, LA van der Poel, W Thornhill… - Archives of Disease in …, 2015 - ep.bmj.com
This review provides an overview of the use of antihistamines in children. We discuss types
of histamine receptors and their mechanism of action, absorption, onset and duration of …

The potassium channel subunit KV3. 1b is localized to somatic and axonal membranes of specific populations of CNS neurons

…, H Baker, D Hillman, S Chen, W Thornhill… - Journal of …, 1995 - Soc Neuroscience
Potassium channels play major roles in the regulation of many aspects of neuronal excitability.
These channels are particularly well suited for such multiplicity of roles since there is a …

G-protein-gated inward rectifier K+ channel proteins (GIRK1) are present in the soma and dendrites as well as in nerve terminals of specific neurons in the brain

…, MB Wu, X Wu, B Rudy, WB Thornhill - Journal of …, 1996 - Soc Neuroscience
G-protein-gated inward rectifier potassium (GIRK) channels are coupled to numerous
neurotransmitter receptors in the brain and can play important roles in modulating neuronal …

[HTML][HTML] Glycosylation affects the protein stability and cell surface expression of Kv1. 4 but not Kv1. 1 potassium channels: a pore region determinant dictates the effect …

…, J Zhu, E Recio-Pinto, WB Thornhill - Journal of Biological …, 2004 - ASBMB
Kv1.1 and Kv1.4 potassium channels are plasma membrane glycoproteins involved in action
potential repolarization. We have shown previously that glycosylation affects the gating …

Neuraminidase treatment modifies the function of electroplax sodium channels in planar lipid bilayers

E Recio-Pinto, WB Thornhill, DS Duch, SR Levinson… - Neuron, 1990 - cell.com
Sodium channels from several sources are covalently modified by unusually large numbers
of negatively charged sialic acid residues. In the present studies, purified electroplax sodium …

The evolutionary psychology of men's coercive sexuality

R Thornhill, NW Thornhill - Behavioral and Brain Sciences, 1992 - cambridge.org
… We have predicted that men of low socioeconomic status will be more inclined to rape (Thornhill
& Thornhill 1983) because they have less access to preferred mates, but because the …

Glycosylation affects rat Kv1. 1 potassium channel gating by a combined surface potential and cooperative subunit interaction mechanism

…, J Zhu, E Recio‐Pinto, WB Thornhill - The Journal of …, 2003 - Wiley Online Library
The effect of glycosylation on Kv1.1 potassium channel function was investigated in
mammalian cells stably transfected with Kv1.1 or Kv1.1N207Q. Macroscopic current analysis …

The glycosylation state of Kv1. 2 potassium channels affects trafficking, gating, and simulated action potentials

…, A Gottschalk, E Recio-Pinto, WB Thornhill - Brain research, 2007 - Elsevier
We presented evidence previously that decreasing the glycosylation state of the Kv1.1 potassium
channel modified its gating by a combined surface potential and a cooperative subunit …

The Kv1. 3 potassium channel is localized to the cis‐Golgi and Kv1. 6 is localized to the endoplasmic reticulum in rat astrocytes

J Zhu, J Yan, WB Thornhill - The FEBS journal, 2014 - Wiley Online Library
ThornhillThornhill … This work was partially supported by NIH grant NS48906 to WB
Thornhill. There are no conflicts of interest associated with this work. …

[HTML][HTML] Expression of Kv1. 1 delayed rectifier potassium channels in Lec mutant Chinese hamster ovary cell lines reveals a role for sialidation in channel function

WB Thornhill, MB Wu, X Jiang, X Wu, PT Morgan… - Journal of Biological …, 1996 - ASBMB
Kv1.1 potassium (K + ) channels contain significant amounts of negatively charged sialic
acids. To examine the role of sialidation in K + channel function, Chinese hamster ovary cell …