True and false memories, parietal cortex, and confidence judgments
- 1Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA
- 2Department of Psychiatry, University of California, San Diego, La Jolla, California 92093, USA
- 3Department of Neurosciences, University of California, San Diego, La Jolla, California 92093, USA
- 4Department of Psychology, University of California, San Diego, La Jolla, California 92093, USA
- Corresponding author: lsquire{at}ucsd.edu
Abstract
Recent studies have asked whether activity in the medial temporal lobe (MTL) and the neocortex can distinguish true memory from false memory. A frequent complication has been that the confidence associated with correct memory judgments (true memory) is typically higher than the confidence associated with incorrect memory judgments (false memory). Accordingly, it has often been difficult to know whether a finding is related to memory confidence or memory accuracy. In the current study, participants made recognition memory judgments with confidence ratings in response to previously studied scenes and novel scenes. The left hippocampus and 16 other brain regions distinguished true and false memories when confidence ratings were different for the two conditions. Only three regions (all in the parietal cortex) distinguished true and false memories when confidence ratings were equated. These findings illustrate the utility of taking confidence ratings into account when identifying brain regions associated with true and false memories. Neural correlates of true and false memories are most easily interpreted when confidence ratings are similar for the two kinds of memories.
Footnotes
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Article is online at http://www.learnmem.org/cgi/doi/10.1101/lm.038349.115.
- Received February 3, 2015.
- Accepted August 11, 2015.
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