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As of July 1, 2025, authors must comply with the new NIH Public Access Policy. For more information on this policy and how to comply with it, see the NIH Public Access Policy section on the Rights and Permissions page.

Current Issue Table of Contents: 5 Nov 2025 Volume 45, Issue 45

The Journal of Neuroscience: 45 (45)

About the Cover

This image from 1945 shows an A-26 Invader prepared for testing in the 40- by 80-foot wind tunnel at the NASA Ames Research Center in California. Today, aircrafts and spacecrafts still undergo tests in wind tunnels. These tests provide important data by balancing real-world complexity with controlled experiments. Just as wind tunnels transformed aviation by taking aerodynamics from theoretical to practical impact, Mohammad Shehata and colleagues argue that neuroscience needs behavioral “wind tunnels” to accelerate its own real-world applicability. See the article by Shehata et al. for more information on how creating more ecologically relevant models of brain function may be vital for advancing neuroscience and benefiting society. Cover image: National Advisory Committee for Aeronautics

New in the Journal

Read the latest Neuro and Beyond paper
Read the latest articles in the Computational Properties of the Prefrontal Cortex Special Collection
Listen to the latest episode of Neuro Current Podcast

Supplemental Material

Featured Articles

  • This Week in The Journal
    This Week in The Journal
    November 05, 2025
  • Research Articles, Cellular/Molecular
    Cofilin Inhibition Ameliorates PIEZO2 and...
    November 05, 2025
  • Research Articles, Systems/Circuits
    Functional Connectivity Is Dominated by Aperiodic, Rather Than Oscillatory, Coupling
    November 05, 2025
  • Viewpoints
    Neuroscience Needs Behavioral “Wind Tunnels” for Real-Life Translation
    November 05, 2025
  • Research Articles, Cellular/Molecular
    TREK1 Channels Shape Spindle-Like Oscillations, Neuronal Activity, and Short-Term Synaptic...
    November 05, 2025
  • Research Articles, Systems/Circuits
    Visual Distortions in Human Amblyopia Are Correlated with Deficits in Contrast Sensitivity
    November 05, 2025
  • Research Articles, Behavioral/Cognitive
    Walking Modulates Active Auditory Sensing
    November 05, 2025
  • Research Articles, Neurobiology of Disease
    Noninvasive Biomarkers for Assessing the Excitatory/Inhibitory Imbalance in Children with Epilepsy
    November 05, 2025

Early Release

  • Research Articles, Behavioral/Cognitive
    Too little and too much: balanced hippocampal, but not medial prefrontal, neural activity is required for intact novel object recognition in rats
    Charlotte J. L. Taylor, Jacco G. Renström, Joanna Loayza, Miriam Gwilt, Stuart A. Williams, Rachel Grasmeder Allen, Paula M. Moran, John Gigg, Joanna Neill, Michael Harte and Tobias Bast
    Journal of Neuroscience 4 November 2025, e1141252025; https://doi.org/10.1523/JNEUROSCI.1141-25.2025
  • Research Articles, Systems/Circuits
    Structural plasticity of peptidergic and nonpeptidergic C afferent terminals in the medullary dorsal horn during craniofacial inflammatory pain
    Yi Sul Cho, Yun Sook Kim, Jin Young Bae, Dong Kuk Ahn, Atsushi Yoshida and Yong Chul Bae
    Journal of Neuroscience 4 November 2025, e1346252025; https://doi.org/10.1523/JNEUROSCI.1346-25.2025
  • Research Articles, Systems/Circuits
    Comparison of signals from cerebellar Purkinje cells and deep nuclei during temporal prediction in primates
    Ken-ichi Okada, Masashi Kameda and Masaki Tanaka
    Journal of Neuroscience 4 November 2025, e1061252025; https://doi.org/10.1523/JNEUROSCI.1061-25.2025
  • Research Articles, Systems/Circuits
    Energy Deficit is a Key Driver of Sleep Homeostasis
    Scarlet J. Park, Keith R. Murphy and William W. Ja
    Journal of Neuroscience 3 November 2025, e1656242025; https://doi.org/10.1523/JNEUROSCI.1656-24.2025
  • Research Articles, Behavioral/Cognitive
    Ventral striatal cholinergic interneurons regulate decision making or motor impulsivity differentially across learning and biological sex
    Tristan J. Hynes, Chloe S. Chernoff, Kelly Hrelja, Andrew Li, Graeme D. Betts, Lucas S. Calderhead and Catharine A. Winstanley
    Journal of Neuroscience 3 November 2025, e0764252025; https://doi.org/10.1523/JNEUROSCI.0764-25.2025
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  • An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
  • The Fusiform Face Area: A Module in Human Extrastriate Cortex Specialized for Face Perception
  • Dissociable Intrinsic Connectivity Networks for Salience Processing and Executive Control
  • A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function
  • Synaptic Modifications in Cultured Hippocampal Neurons: Dependence on Spike Timing, Synaptic Strength, and Postsynaptic Cell Type
More...
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