Register for the next episode of SfN Journals: In Conversation, on Input-Independent Homeostasis of Developing Thalamocortical Activity, June 22 at 12 PM ET
About the Cover
This image shows accumulation of polyglutamine-expanded ATXN7 (red) in CALB1-immunostained Purkinje neurons (green) in cerebellum in a mouse model of spinocerebellar ataxia type 7. This abnormal accumulation leads to the progressive downregulation of 83 Purkinje identity genes critical for spontaneous firing activity and synaptic functions. For more information, see the article by Niewiadomska-Cimicka et al. (pages 4910–4936). Cover image: Anna Niewiadomska-Cimicka.
