Naturally Occurring Truncated trkB Receptors Have Dominant Inhibitory Effects on Brain-Derived Neurotrophic Factor Signaling

This research was supported by National Institute on Aging Grant K11AG00568 (F.F.E.), a seed Grant from the Brain Research Foundation, and National Institutes of Mental Health Grant 48200. L.F. Reichardt is an investigator of The Howard Hughes Medical Institute. We thank Drs. R. Kypta, G. Lopez, A. MacNicol, U. Muller, and A. Muslin for many helpful discussions and comments. We also thank Drs. J. Escobedo, T. Hunter, D. Middlemas, W. Mobley, P. Olson, and A. Rosenthal for their generous gifts of constructs and reagents.

Correspondence should be addressed to Dr. Fernette F. Eide, Department of Neurology, MC 2030, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637.