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Articles

Translocation of RNA Granules in Living Neurons

Roger B. Knowles, James H. Sabry, Maryann E. Martone, Thomas J. Deerinck, Mark H. Ellisman, Gary J. Bassell and Kenneth S. Kosik
Journal of Neuroscience 15 December 1996, 16 (24) 7812-7820; DOI: https://doi.org/10.1523/JNEUROSCI.16-24-07812.1996
Roger B. Knowles
1Center for Neurological Diseases, Brigham and Women’s Hospital, Boston, Massachusetts 02115,
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James H. Sabry
2Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, and
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Maryann E. Martone
3Microscopy and Imaging Resource, University of California, San Diego, La Jolla, California 92093-0608
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Thomas J. Deerinck
3Microscopy and Imaging Resource, University of California, San Diego, La Jolla, California 92093-0608
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Mark H. Ellisman
3Microscopy and Imaging Resource, University of California, San Diego, La Jolla, California 92093-0608
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Gary J. Bassell
1Center for Neurological Diseases, Brigham and Women’s Hospital, Boston, Massachusetts 02115,
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Kenneth S. Kosik
1Center for Neurological Diseases, Brigham and Women’s Hospital, Boston, Massachusetts 02115,
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.16-24-07812.1996
PubMed 
8987809
Published By 
Society for Neuroscience
History 
  • Received July 10, 1996
  • Revision received September 13, 1996
  • Accepted September 24, 1996
  • First published December 15, 1996.
  • Version of record published December 15, 1996.
Copyright & Usage 
Copyright © 1996 Society for Neuroscience

Author Information

  1. Roger B. Knowles1,
  2. James H. Sabry2,
  3. Maryann E. Martone3,
  4. Thomas J. Deerinck3,
  5. Mark H. Ellisman3,
  6. Gary J. Bassell1, and
  7. Kenneth S. Kosik1
  1. 1Center for Neurological Diseases, Brigham and Women’s Hospital, Boston, Massachusetts 02115,
  2. 2Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, and
  3. 3Microscopy and Imaging Resource, University of California, San Diego, La Jolla, California 92093-0608
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Author contributions

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Disclosures

    • Received July 10, 1996.
    • Revision received September 13, 1996.
    • Accepted September 24, 1996.
  • This work was supported by National Institutes of Health Grant NS29031 and the American Health Assistance Foundation to K.S.K. and National Institutes of Health, National Center for Research Resources, P41 04050 to M.H.E. We thank Marc Kirschner for generously allowing the use of microscopy equipment for some of these experiments. Antibody to EF1α was kindly provided by Wim Moller (Rijks University, Leiden, The Netherlands), and antibody to 60S ribosomal subunit was generously provided by John Hesketh (Rowett Research Institute, Aberdeen, UK). We thank Ying Zhang for her technical support.

    Correspondence should be addressed to Dr. Kenneth S. Kosik, Brigham and Women’s Hospital, 221 Longwood Avenue, Boston, MA 02115.

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Jan 19992148
Feb 1999343
Mar 199971413
Dec 199911311
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Jan 200011714
Feb 200051915
Mar 200071924
Apr 200032020
May 200082931
Jun 200022226
Jul 200041811
Aug 200021511
Sep 200042014
Oct 200071513
Nov 200093622
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Total 200055239207
Jan 200154831
Feb 200112021
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Apr 200143515
May 200122416
Jun 20016219
Jul 200121714
Aug 200114128
Sep 200122815
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Feb 200213824
Mar 200254529
Apr 200233231
May 200211429
Jun 200272618
Jul 200222626
Aug 200212229
Sep 200223029
Oct 200265879
Nov 200214334
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Total 200232396382
Jan 200312222
Feb 200362724
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Apr 200323221
May 2003115039
Jun 200392418
Jul 2003154720
Aug 2003133623
Sep 2003196631
Oct 2003197539
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Total 2003147503315
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Feb 2004192625
Mar 2004243515
Apr 2004363315
May 2004214734
Jun 2004175132
Jul 2004183526
Aug 2004183518
Sep 2004248720
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Total 2004265506260
Jan 2005286233
Feb 2005233927
Mar 2005254032
Apr 2005133340
May 2005102227
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Jul 2005182629
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Apr 2006102928
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Feb 200783329
Mar 2007103321
Apr 200782836
May 200752730
Jun 200783938
Jul 200761818
Aug 200772123
Sep 200752917
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Nov 200764424
Dec 200731713
Total 200788362313
Jan 200891922
Feb 200891311
Mar 200891817
Apr 2008104034
May 2008161721
Jun 2008101820
Jul 200892315
Aug 2008102521
Sep 2008161510
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Total 2008133245230
Jan 200932018
Feb 200982127
Mar 200972715
Apr 2009142424
May 2009111421
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Jul 200951616
Aug 2009352127
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Total 2009158267301
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Total 2010119280282
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Jul 2011152117
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Sep 2011191927
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Total 2011194212261
Jan 2012132729
Feb 2012171730
Mar 2012231832
Apr 2012111632
May 2012202123
Jun 2012181320
Jul 2012151524
Aug 201281213
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Total 2012214186304
Jan 2013151020
Feb 2013141320
Mar 2013222225
Apr 2013184125
May 2013131312
Jun 2013201035
Jul 201311719
Aug 20135515
Sep 2013121321
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Total 2013166172244
Jan 2014171721
Feb 201414626
Mar 201420928
Apr 2014141215
May 2014161726
Jun 201420614
Jul 2014293015
Aug 201471119
Sep 2014201123
Oct 2014121117
Nov 2014201117
Dec 201416916
Total 2014205150237
Jan 2015141715
Feb 2015121617
Mar 2015261820
Apr 201514129
May 2015202615
Jun 201514129
Jul 2015143415
Aug 201513147
Sep 2015122711
Oct 2015171318
Nov 2015133019
Dec 2015242015
Total 2015193239170
Jan 2016141211
Feb 2016321826
Mar 2016293627
Apr 2016134019
May 2016154413
Jun 2016173118
Jul 2016162119
Aug 2016232218
Sep 2016112318
Oct 201691812
Nov 201682017
Dec 201652010
Total 2016192305208
Jan 201762812
Feb 201772917
Mar 201712823
Apr 201782264
May 2017115828
Jun 20171188
Jul 201742819
Aug 201782819
Sep 201742413
Oct 201713122
Nov 201753619
Dec 20174125
Total 201760342249
Jan 20184214
Feb 2018121913
Mar 201872413
Apr 201853422
May 201893919
Jun 201874821
Jul 201862111
Aug 201813514
Sep 201836615
Oct 201875713
Nov 20182506
Dec 20186358
Total 201869449159
Jan 201943414
Feb 2019104615
Mar 201972416
Apr 2019111920
May 201982620
Jun 201992619
Jul 201954023
Aug 201962721
Sep 201936010
Oct 20192812126
Nov 2019123520
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Total 2019108504219
Jan 202073617
Feb 202018137
Mar 202082624
Apr 2020101013
May 202012249
Jun 20206128
Jul 202061910
Aug 202061411
Sep 202044519
Oct 202043915
Nov 2020114716
Dec 2020113714
Total 2020103322163
Jan 20211207
Total 20211207
Total291069425432
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In this issue

The Journal of Neuroscience: 16 (24)
Journal of Neuroscience
Vol. 16, Issue 24
15 Dec 1996
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Translocation of RNA Granules in Living Neurons
Roger B. Knowles, James H. Sabry, Maryann E. Martone, Thomas J. Deerinck, Mark H. Ellisman, Gary J. Bassell, Kenneth S. Kosik
Journal of Neuroscience 15 December 1996, 16 (24) 7812-7820; DOI: 10.1523/JNEUROSCI.16-24-07812.1996

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Translocation of RNA Granules in Living Neurons
Roger B. Knowles, James H. Sabry, Maryann E. Martone, Thomas J. Deerinck, Mark H. Ellisman, Gary J. Bassell, Kenneth S. Kosik
Journal of Neuroscience 15 December 1996, 16 (24) 7812-7820; DOI: 10.1523/JNEUROSCI.16-24-07812.1996
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Keywords

  • RNA granules
  • cytoskeleton
  • ribosomes
  • β-actin mRNA
  • elongation factor 1α
  • photo-oxidation
  • RNA translocation

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