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Articles

Sonic Hedgehog Promotes the Survival of Specific CNS Neuron Populations and Protects These Cells from Toxic Insult In Vitro

Ningning Miao, Monica Wang, Jennifer A. Ott, Josephine S. D’Alessandro, Tod M. Woolf, David A. Bumcrot, Nagesh K. Mahanthappa and Kevin Pang
Journal of Neuroscience 1 August 1997, 17 (15) 5891-5899; DOI: https://doi.org/10.1523/JNEUROSCI.17-15-05891.1997
Ningning Miao
1Ontogeny, Inc., Cambridge, Massachusetts 02138
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Monica Wang
1Ontogeny, Inc., Cambridge, Massachusetts 02138
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Jennifer A. Ott
1Ontogeny, Inc., Cambridge, Massachusetts 02138
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Josephine S. D’Alessandro
1Ontogeny, Inc., Cambridge, Massachusetts 02138
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Tod M. Woolf
1Ontogeny, Inc., Cambridge, Massachusetts 02138
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David A. Bumcrot
1Ontogeny, Inc., Cambridge, Massachusetts 02138
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Nagesh K. Mahanthappa
1Ontogeny, Inc., Cambridge, Massachusetts 02138
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Kevin Pang
1Ontogeny, Inc., Cambridge, Massachusetts 02138
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.17-15-05891.1997
PubMed 
9221786
Published By 
Society for Neuroscience
History 
  • Received February 26, 1997
  • Revision received May 16, 1997
  • Accepted May 20, 1997
  • First published August 1, 1997.
  • Version of record published August 1, 1997.
Copyright & Usage 
Copyright © 1997 Society for Neuroscience

Author Information

  1. Ningning Miao,
  2. Monica Wang,
  3. Jennifer A. Ott,
  4. Josephine S. D’Alessandro,
  5. Tod M. Woolf,
  6. David A. Bumcrot,
  7. Nagesh K. Mahanthappa, and
  8. Kevin Pang
  1. 1Ontogeny, Inc., Cambridge, Massachusetts 02138
View Full Text

Author contributions

Disclosures

    • Received February 26, 1997.
    • Revision received May 16, 1997.
    • Accepted May 20, 1997.
  • We thank Drs. D. Melton, T. Jessell, C. Tabin, and T. Ingolia for critical review of this manuscript; A. McMahon and M. Scott forin situ probe templates; A. McMahon and T. Jessell for antibodies; and H. Roelink for Shh-encoding baculovirus. We also thank P. Jin for advice on QC-PCR.

    Correspondence should be addressed to Kevin Pang, Ontogeny, Inc., 45 Moulton Street, Cambridge, MA 02138.

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Jan 19990106
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Feb 20002198
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Apr 200011211
May 20003910
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Jul 2000192
Aug 2000388
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Feb 2001285
Mar 2001195
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May 200111811
Jun 2001277
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Aug 2001072
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May 200211016
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Aug 20022815
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Apr 20030610
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Jul 2005161710
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Jun 200731710
Jul 20075117
Aug 2007476
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Feb 2008698
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Apr 2008798
May 200861310
Jun 2008141214
Jul 200841110
Aug 2008188
Sep 2008745
Oct 2008211313
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Mar 200941012
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Jun 2009489
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Total 20096588100
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Total 2012156138174
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Apr 20139715
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Total 20147673336
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Feb 201511737
Mar 201561021
Apr 201541320
May 201521218
Jun 20151613
Jul 20156109
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Sep 20156520
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Feb 201691323
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Apr 20166916
May 2016578
Jun 201661614
Jul 201651110
Aug 201610811
Sep 2016368
Oct 2016171211
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Total 201688130198
Jan 201731727
Feb 20173816
Mar 201742528
Apr 201751423
May 201753411
Jun 20174109
Jul 20174145
Aug 20177139
Sep 20176117
Oct 2017486
Nov 20174147
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Total 201756177153
Jan 201851110
Feb 2018787
Mar 2018587
Apr 20186157
May 20185206
Jun 20186237
Jul 201811108
Aug 20185116
Sep 20186205
Oct 20184124
Nov 20184136
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Total 20187016681
Jan 20195106
Feb 20194123
Mar 20195145
Apr 20196105
May 20195124
Jun 20192148
Jul 201961210
Aug 20194115
Sep 2019295
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Nov 20196119
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Total 20195615471
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Feb 20203135
Mar 2020363
Apr 20200181
May 20203213
Jun 20201453
Jul 20201376
Aug 20201132
Sep 202042111
Oct 20201236
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Total 20202925363
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Feb 20213173
Mar 202134517
Apr 20212234
Total 2021811266
Total166034303008
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The Journal of Neuroscience: 17 (15)
Journal of Neuroscience
Vol. 17, Issue 15
1 Aug 1997
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Sonic Hedgehog Promotes the Survival of Specific CNS Neuron Populations and Protects These Cells from Toxic Insult In Vitro
Ningning Miao, Monica Wang, Jennifer A. Ott, Josephine S. D’Alessandro, Tod M. Woolf, David A. Bumcrot, Nagesh K. Mahanthappa, Kevin Pang
Journal of Neuroscience 1 August 1997, 17 (15) 5891-5899; DOI: 10.1523/JNEUROSCI.17-15-05891.1997

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Sonic Hedgehog Promotes the Survival of Specific CNS Neuron Populations and Protects These Cells from Toxic Insult In Vitro
Ningning Miao, Monica Wang, Jennifer A. Ott, Josephine S. D’Alessandro, Tod M. Woolf, David A. Bumcrot, Nagesh K. Mahanthappa, Kevin Pang
Journal of Neuroscience 1 August 1997, 17 (15) 5891-5899; DOI: 10.1523/JNEUROSCI.17-15-05891.1997
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Keywords

  • sonic hedgehog
  • patched
  • midbrain
  • striatum
  • spinal cord
  • Parkinson’s disease

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