Mutation Causing Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Alters Ca²⁺ Permeability, Conductance, and Gating of Human α4β2 Nicotinic Acetylcholine Receptors

This work was supported by grants to J.L. from the National Institutes of Health (NS11323), the Smokeless Tobacco Research Council, Incorporated, and the Muscular Dystrophy Association. M.N. was supported by a National Research Service Award fellowship.

A.K., V.G., and M.N. contributed equally to this work.

Correspondence should be addressed to Dr. Jon Lindstrom, 217 Stemmler Hall, Department of Neuroscience, Medical School of the University of Pennsylvania, Philadelphia, PA 19104-6074.