Article Figures & Data
Figures
- Fig. 1.
Double-plotted actograms of two hamsters that received melatonin injections in the morning (circles) and vehicle (diamonds) in the evening (group 1) for 7 d immediately after transplantation (T). The hamsters also received injections (as indicated) 6 weeks after transplantation. Theheavy vertical lines are the eye fit lines used to estimate the phases of activity onset on the day after the initial set of injections (top end of the line).Asterisks on the time scales at the tops of the actograms also indicate the phases. Eye fit lines before and after the later set of injections were used to assess the effects of the injections. In most cases these two lines appear as a single line, because no shifts or changes in period occurred. The VIP-immunoreactive grafts of animals A and B are shown in Figure 3, A andB.
- Fig. 2.
Double-plotted actograms of two hamsters that received melatonin injections in the evening (circles) and vehicle (diamonds) in the morning (group 2) for 7 days immediately after transplantation (T). The hamsters also received injections (as indicated) 6 weeks after transplantation. Theheavy vertical lines are the eye fit lines used to estimate the phases of activity onset on the day after the initial set of injections (top end of the line).Asterisks on the time scales at the tops of the actograms also indicate the phases. Eye fit lines before and after the later set of injections were used to assess the effects of the later injections. Record B shows an advance phase shift in response to vehicle injections. The VIP-immunoreactive grafts of animals A and B are shown in Figure 3, C andD.
- Fig. 3.
Photomicrographs of coronal sections that contained grafted tissue with VIP immunoreactivity (arrows)in four of the hamsters from the study. Lesions of the host SCN can also be seen in A and D. Och, Optic chiasm;3V, third ventricle.
- Fig. 4.
Phases of activity onset on the day after the final injection for all animals plotted on a circle representing the 24 hr of that day. Open circles represent individual animals that received melatonin in the morning and vehicle in the evening (group 1), and closed circles represent animals that received vehicle in the morning and melatonin in the evening (group 2). The average phase for each group is shown by the arrows within the circle (open arrow, group 1;closed arrow, group 2), and the degree of synchrony within each group is represented by the length of thearrows and by the value of r. Arrows outside the circle indicate the times of the injections.
