Three-Dimensional Structure and Composition of CA3→CA1 Axons in Rat Hippocampal Slices: Implications for Presynaptic Connectivity and Compartmentalization

This work was supported by National Institutes of Health Grants NS21184 and MH/DA57351, with the latter funded jointly by the National Institute of Mental Health, National Institute on Drug Abuse, and NASA (K.M.H.); and by the Mental Retardation Research Center Grant P30-HD18655 (Dr. Joseph Volpe, Principal Investigator). We thank Sergei Kirov for preparing the hippocampal slices, Marcia Feinberg for expert serial EM technical assistance, John Fiala for creation of the IGL Trace reconstruction system, and John Fiala and Karin Sorra for helpful comments on this paper.

Correspondence should be addressed to Kristen M. Harris, Ph.D., Department of Neurology, Children’s Hospital, Enders 208, 300 Longwood Avenue, Boston, MA 02115.