Massive Mitochondrial Degeneration in Motor Neurons Triggers the Onset of Amyotrophic Lateral Sclerosis in Mice Expressing a Mutant SOD1

This work is supported by grants from National Institutes of Health (RO1NS35750-01), the ALS Association, and the Markey Charitable Trust. We thank Vivian Tung for technical assistance and Alonzo Ross and Diane Casey for critically reading this manuscript.

Correspondence should be addressed to Zuoshang Xu, Worcester Foundation, 222 Maple Avenue, Shrewsbury, MA 01545.