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ARTICLE

Song-Induced Phosphorylation of cAMP Response Element-Binding Protein in the Songbird Brain

Hironobu Sakaguchi, Kazuhiro Wada, Masao Maekawa, Toshikazu Watsuji and Masatoshi Hagiwara
Journal of Neuroscience 15 May 1999, 19 (10) 3973-3981; https://doi.org/10.1523/JNEUROSCI.19-10-03973.1999
Hironobu Sakaguchi
1Department of Physiology, Dokkyo University, School of Medicine, and
2Intelligence and Synthesis, Precursory Research for Embryonic Science and Technology, Japan Science and Technology Corporation, Mibu, Tochigi 321–0293, Japan, and
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Kazuhiro Wada
3Department of Functional Genomics, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113–8519, Japan
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Masao Maekawa
1Department of Physiology, Dokkyo University, School of Medicine, and
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Toshikazu Watsuji
3Department of Functional Genomics, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113–8519, Japan
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Masatoshi Hagiwara
3Department of Functional Genomics, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113–8519, Japan
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.19-10-03973.1999
PubMed 
10234027
Published By 
Society for Neuroscience
History 
  • Received September 23, 1998
  • Revision received February 26, 1999
  • Accepted March 2, 1999
  • First published May 15, 1999.
  • Version of record published May 15, 1999.
Copyright & Usage 
Copyright © 1999 Society for Neuroscience

Author Information

  1. Hironobu Sakaguchi1,2,
  2. Kazuhiro Wada3,
  3. Masao Maekawa1,
  4. Toshikazu Watsuji3, and
  5. Masatoshi Hagiwara3
  1. 1Department of Physiology, Dokkyo University, School of Medicine, and
  2. 2Intelligence and Synthesis, Precursory Research for Embryonic Science and Technology, Japan Science and Technology Corporation, Mibu, Tochigi 321–0293, Japan, and
  3. 3Department of Functional Genomics, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113–8519, Japan
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Author contributions

Disclosures

    • Received September 23, 1998.
    • Revision received February 26, 1999.
    • Accepted March 2, 1999.
  • This work was supported in part by a grant from the Ministry of Education, Science and Culture in Japan. We thank Dr. M. Montminy (Harvard University, Cambridge, MA) for providing antiserum 5322; Dr. K. Dong (Kobe University, Japan) for providing the FRe; Dr. R. Li (Tokyo University, Japan) for her technical advice; R. Kawakubo for drawing figures; Dr. I. Taniguchi (Tokyo Medical and Dental University) for his encouragement during this work; and Dr. J. L. Maderdrut (Tulane University, New Orleans, LA) for improving this manuscript.

    Correspondence should be addressed to Dr. Masatoshi Hagiwara, Department of Functional Genomics, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8519, Japan, or Dr. Hironobu Sakaguchi, Department of Physiology, Dokkyo University, School of Medicine, Mibu, Tochigi 321-0293, Japan.

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The Journal of Neuroscience: 19 (10)
Journal of Neuroscience
Vol. 19, Issue 10
15 May 1999
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Song-Induced Phosphorylation of cAMP Response Element-Binding Protein in the Songbird Brain
Hironobu Sakaguchi, Kazuhiro Wada, Masao Maekawa, Toshikazu Watsuji, Masatoshi Hagiwara
Journal of Neuroscience 15 May 1999, 19 (10) 3973-3981; DOI: 10.1523/JNEUROSCI.19-10-03973.1999

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Song-Induced Phosphorylation of cAMP Response Element-Binding Protein in the Songbird Brain
Hironobu Sakaguchi, Kazuhiro Wada, Masao Maekawa, Toshikazu Watsuji, Masatoshi Hagiwara
Journal of Neuroscience 15 May 1999, 19 (10) 3973-3981; DOI: 10.1523/JNEUROSCI.19-10-03973.1999
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Keywords

  • CREB
  • birdsong
  • zebra finch
  • higher vocal center
  • phosphorylation
  • transcription factor

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