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ARTICLE

Adult Mammalian Forebrain Ependymal and Subependymal Cells Demonstrate Proliferative Potential, but only Subependymal Cells Have Neural Stem Cell Characteristics

Bernard J. Chiasson, Vincent Tropepe, Cindi M. Morshead and Derek van der Kooy
Journal of Neuroscience 1 June 1999, 19 (11) 4462-4471; https://doi.org/10.1523/JNEUROSCI.19-11-04462.1999
Bernard J. Chiasson
1Neurobiology Research Group, Department of Anatomy and Cell Biology, University of Toronto, Toronto, Canada, M5S 1A8
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Vincent Tropepe
1Neurobiology Research Group, Department of Anatomy and Cell Biology, University of Toronto, Toronto, Canada, M5S 1A8
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Cindi M. Morshead
1Neurobiology Research Group, Department of Anatomy and Cell Biology, University of Toronto, Toronto, Canada, M5S 1A8
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Derek van der Kooy
1Neurobiology Research Group, Department of Anatomy and Cell Biology, University of Toronto, Toronto, Canada, M5S 1A8
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.19-11-04462.1999
PubMed 
10341247
Published By 
Society for Neuroscience
History 
  • Received November 2, 1998
  • Revision received March 15, 1999
  • Accepted March 22, 1999
  • First published June 1, 1999.
  • Version of record published June 1, 1999.
Copyright & Usage 
Copyright © 1999 Society for Neuroscience

Author Information

  1. Bernard J. Chiasson,
  2. Vincent Tropepe,
  3. Cindi M. Morshead, and
  4. Derek van der Kooy
  1. 1Neurobiology Research Group, Department of Anatomy and Cell Biology, University of Toronto, Toronto, Canada, M5S 1A8
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Author contributions

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Disclosures

    • Received November 2, 1998.
    • Revision received March 15, 1999.
    • Accepted March 22, 1999.
  • This work was supported by the Multiple Sclerosis Society of Canada, Medical Research Council (MRC) and National Centres of Excellence postdoctoral fellowships to B.J.C, an MRC postdoctoral fellowship to C.M.M., and an MRC doctoral research award to V.T. We thank Brenda Coles and Esther Galindo for excellent technical assistance.

    Correspondence should be addressed to Dr. van der Kooy at the above address.

    Dr. Chiasson’s present address: Novartis Pharmaceuticals Canada Inc., 790 Bay Street, Toronto, Canada M5G 1N8.

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The Journal of Neuroscience: 19 (11)
Journal of Neuroscience
Vol. 19, Issue 11
1 Jun 1999
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Adult Mammalian Forebrain Ependymal and Subependymal Cells Demonstrate Proliferative Potential, but only Subependymal Cells Have Neural Stem Cell Characteristics
Bernard J. Chiasson, Vincent Tropepe, Cindi M. Morshead, Derek van der Kooy
Journal of Neuroscience 1 June 1999, 19 (11) 4462-4471; DOI: 10.1523/JNEUROSCI.19-11-04462.1999

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Adult Mammalian Forebrain Ependymal and Subependymal Cells Demonstrate Proliferative Potential, but only Subependymal Cells Have Neural Stem Cell Characteristics
Bernard J. Chiasson, Vincent Tropepe, Cindi M. Morshead, Derek van der Kooy
Journal of Neuroscience 1 June 1999, 19 (11) 4462-4471; DOI: 10.1523/JNEUROSCI.19-11-04462.1999
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Keywords

  • ependyma
  • subependyma
  • neural stem cells
  • proliferation
  • adult
  • forebrain

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