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ARTICLE, DEVELOPMENTAL

Growth Factors and Taurine Protect against Excitotoxicity by Stabilizing Calcium Homeostasis and Energy Metabolism

Abdeslem El Idrissi and Ekkhart Trenkner
Journal of Neuroscience 1 November 1999, 19 (21) 9459-9468; https://doi.org/10.1523/JNEUROSCI.19-21-09459.1999
Abdeslem El Idrissi
1New York State Institute for Basic Research in Developmental Disabilities, Center for Developmental Neuroscience, The Graduate School and University Center of the City University of New York, Staten Island, New York 10314
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Ekkhart Trenkner
1New York State Institute for Basic Research in Developmental Disabilities, Center for Developmental Neuroscience, The Graduate School and University Center of the City University of New York, Staten Island, New York 10314
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.19-21-09459.1999
PubMed 
10531449
Published By 
Society for Neuroscience
History 
  • Received June 4, 1999
  • Revision received August 13, 1999
  • Accepted August 20, 1999
  • First published November 1, 1999.
  • Version of record published November 1, 1999.
Copyright & Usage 
Copyright © 1999 Society for Neuroscience

Author Information

  1. Abdeslem El Idrissi and
  2. Ekkhart Trenkner
  1. 1New York State Institute for Basic Research in Developmental Disabilities, Center for Developmental Neuroscience, The Graduate School and University Center of the City University of New York, Staten Island, New York 10314
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Author contributions

Disclosures

    • Received June 4, 1999.
    • Revision received August 13, 1999.
    • Accepted August 20, 1999.
  • This study was supported in part by funds from the New York State Office of Mental Retardation and Developmental Disabilities and the Center of Developmental Neuroscience and Developmental Disabilities. We are grateful to Drs A. Rabe, T. Lidsky, and M. Quinn for their time to critically read and discuss this manuscript with us and for their suggestions to make it readable.

    Correspondence should be addressed to Dr. Ekkehart Trenkner, Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314. E-mail: trenkner{at}postbox.csi.cuny.eduand trenkner{at}hotmail.com.

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The Journal of Neuroscience: 19 (21)
Journal of Neuroscience
Vol. 19, Issue 21
1 Nov 1999
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Growth Factors and Taurine Protect against Excitotoxicity by Stabilizing Calcium Homeostasis and Energy Metabolism
Abdeslem El Idrissi, Ekkhart Trenkner
Journal of Neuroscience 1 November 1999, 19 (21) 9459-9468; DOI: 10.1523/JNEUROSCI.19-21-09459.1999

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Growth Factors and Taurine Protect against Excitotoxicity by Stabilizing Calcium Homeostasis and Energy Metabolism
Abdeslem El Idrissi, Ekkhart Trenkner
Journal of Neuroscience 1 November 1999, 19 (21) 9459-9468; DOI: 10.1523/JNEUROSCI.19-21-09459.1999
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Keywords

  • cerebellar granule cells
  • excitotoxicity
  • growth factors
  • taurine
  • glutamate
  • calcium
  • energy metabolism
  • BDNF
  • bFGF

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