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ARTICLE, Cellular/Molecular

α1E Subunits Form the Pore of Three Cerebellar R-Type Calcium Channels with Different Pharmacological and Permeation Properties

Angelita Tottene, Stephen Volsen and Daniela Pietrobon
Journal of Neuroscience 1 January 2000, 20 (1) 171-178; https://doi.org/10.1523/JNEUROSCI.20-01-00171.2000
Angelita Tottene
1Department of Biomedical Sciences, University of Padova, 35121 Padova, Italy, and
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Stephen Volsen
2Lilly Research Center, Eli Lilly Company Limited, Windlesham, Surrey GU20 6PH, United Kingdom
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Daniela Pietrobon
1Department of Biomedical Sciences, University of Padova, 35121 Padova, Italy, and
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.20-01-00171.2000
PubMed 
10627594
Published By 
Society for Neuroscience
History 
  • Received August 9, 1999
  • Revision received October 18, 1999
  • Accepted October 20, 1999
  • First published January 1, 2000.
  • Version of record published January 1, 2000.
Copyright & Usage 
Copyright © 2000 Society for Neuroscience

Author Information

  1. Angelita Tottene1,
  2. Stephen Volsen2, and
  3. Daniela Pietrobon1
  1. 1Department of Biomedical Sciences, University of Padova, 35121 Padova, Italy, and
  2. 2Lilly Research Center, Eli Lilly Company Limited, Windlesham, Surrey GU20 6PH, United Kingdom
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Author contributions

Disclosures

    • Received August 9, 1999.
    • Revision received October 18, 1999.
    • Accepted October 20, 1999.
  • This work was supported by Telethon-Italy Grant 720 to D.P. A.T. was supported by the Lilly Postdoctoral Research Program. We thank Drs. G. Miljanich and L. Nadasdi of Elan Pharmaceuticals Inc. for providing SNX483, and Carlo Berizzi and Francesca Bolcato for help in performing some of the experiments.

    Correspondence should be addressed to Daniela Pietrobon, Department of Biomedical Sciences, University of Padova, V.le G. Colombo 3, 35121 Padova, Italy. E-mail: dani{at}civ.bio.unipd.it.

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The Journal of Neuroscience: 20 (1)
Journal of Neuroscience
Vol. 20, Issue 1
1 Jan 2000
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α1E Subunits Form the Pore of Three Cerebellar R-Type Calcium Channels with Different Pharmacological and Permeation Properties
Angelita Tottene, Stephen Volsen, Daniela Pietrobon
Journal of Neuroscience 1 January 2000, 20 (1) 171-178; DOI: 10.1523/JNEUROSCI.20-01-00171.2000

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α1E Subunits Form the Pore of Three Cerebellar R-Type Calcium Channels with Different Pharmacological and Permeation Properties
Angelita Tottene, Stephen Volsen, Daniela Pietrobon
Journal of Neuroscience 1 January 2000, 20 (1) 171-178; DOI: 10.1523/JNEUROSCI.20-01-00171.2000
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Keywords

  • calcium channel
  • α1E subunit
  • antisense oligonucleotides
  • cerebellum
  • granule cells
  • permeation
  • toxin-resistant calcium current

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