ARTICLE, Cellular/Molecular

Evidence for Seeding of β-Amyloid by Intracerebral Infusion of Alzheimer Brain Extracts in β-Amyloid Precursor Protein-Transgenic Mice

Michael D. Kane, William J. Lipinski, Michael J. Callahan, Feng Bian, Robert A. Durham, Roy D. Schwarz, Alex E. Roher and Lary C. Walker
Journal of Neuroscience 15 May 2000, 20 (10) 3606-3611; https://doi.org/10.1523/JNEUROSCI.20-10-03606.2000

Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.20-10-03606.2000
PubMed 
10804202
Published By 
Society for Neuroscience
History 
  • Received December 23, 1999
  • Revision received February 16, 2000
  • Accepted February 29, 2000
  • First published May 15, 2000.
  • Version of record published May 15, 2000.
Copyright & Usage 
Copyright © 2000 Society for Neuroscience

Author Information

  1. Michael D. Kane1,
  2. William J. Lipinski1,
  3. Michael J. Callahan1,
  4. Feng Bian1,
  5. Robert A. Durham1,
  6. Roy D. Schwarz1,
  7. Alex E. Roher2, and
  8. Lary C. Walker1
  1. 1Neuroscience Therapeutics, Parke-Davis Research, Division of Warner-Lambert, Ann Arbor, Michigan 48105, and
  2. 2Haldeman Laboratory for Alzheimer's Disease Research, Sun Health Research Institute, Sun City, Arizona 85372
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Author contributions

Disclosures

    • Received December 23, 1999.
    • Revision received February 16, 2000.
    • Accepted February 29, 2000.

  • We gratefully acknowledge the recommendations of Drs. Byron Caughey and Richard Race (National Institute of Allergy and Infectious Diseases) on the brain extract-preparation methods and the helpful comments of Drs. Mathias Jucker and Scott Baron.

    Correspondence should be addressed to Lary C. Walker, Neuroscience Therapeutics, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert, 2800 Plymouth Road, Ann Arbor, MI 48105. E-mail:lary.walker{at}wl.com.

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Evidence for Seeding of β-Amyloid by Intracerebral Infusion of Alzheimer Brain Extracts in β-Amyloid Precursor Protein-Transgenic Mice
Michael D. Kane, William J. Lipinski, Michael J. Callahan, Feng Bian, Robert A. Durham, Roy D. Schwarz, Alex E. Roher, Lary C. Walker
Journal of Neuroscience 15 May 2000, 20 (10) 3606-3611; DOI: 10.1523/JNEUROSCI.20-10-03606.2000
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