ARTICLE, Cellular/Molecular

Homocysteine Elicits a DNA Damage Response in Neurons That Promotes Apoptosis and Hypersensitivity to Excitotoxicity

Inna I. Kruman, Carsten Culmsee, Sic L. Chan, Yuri Kruman, Zhihong Guo, LaRoy Penix and Mark P. Mattson
Journal of Neuroscience 15 September 2000, 20 (18) 6920-6926; https://doi.org/10.1523/JNEUROSCI.20-18-06920.2000

Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.20-18-06920.2000
PubMed 
10995836
Published By 
Society for Neuroscience
History 
  • Received March 16, 2000
  • Revision received June 21, 2000
  • Accepted July 6, 2000
  • First published September 15, 2000.
  • Version of record published September 15, 2000.
Copyright & Usage 
Copyright © 2000 Society for Neuroscience

Author Information

  1. Inna I. Kruman1,
  2. Carsten Culmsee2,
  3. Sic L. Chan1,
  4. Yuri Kruman1,
  5. Zhihong Guo1,
  6. LaRoy Penix2, and
  7. Mark P. Mattson1,2
  1. 1Laboratory of Neurosciences, National Institute on Aging, Baltimore, Maryland 21224, and
  2. 2Sanders-Brown Research Center on Aging and Department of Anatomy and Neurobiology, University of Kentucky, Lexington, Kentucky 40536
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Author contributions

Disclosures

    • Received March 16, 2000.
    • Revision received June 21, 2000.
    • Accepted July 6, 2000.

  • This work was supported by the National Institute on Aging. We thank M. Juhasova and M. Killen for technical assistance.

    Correspondence should be addressed to Dr. Mark P. Mattson, Laboratory of Neurosciences, National Institute on Aging Gerontology Research Center, 5600 Nathan Shock Drive, Baltimore, MD 21224. E-mail:mattsonm{at}grc.nia.nih.gov.

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Total108138671773
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Homocysteine Elicits a DNA Damage Response in Neurons That Promotes Apoptosis and Hypersensitivity to Excitotoxicity
Inna I. Kruman, Carsten Culmsee, Sic L. Chan, Yuri Kruman, Zhihong Guo, LaRoy Penix, Mark P. Mattson
Journal of Neuroscience 15 September 2000, 20 (18) 6920-6926; DOI: 10.1523/JNEUROSCI.20-18-06920.2000
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