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ARTICLE, Cellular/Molecular

Mutants of a Temperature-Sensitive Two-P Domain Potassium Channel

Maya T. Kunkel, Duncan B. Johnstone, James H. Thomas and Lawrence Salkoff
Journal of Neuroscience 15 October 2000, 20 (20) 7517-7524; https://doi.org/10.1523/JNEUROSCI.20-20-07517.2000
Maya T. Kunkel
1Departments of Anatomy and Neurobiology and
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Duncan B. Johnstone
3Department of Genetics, University of Washington, Seattle, Washington 98195
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James H. Thomas
3Department of Genetics, University of Washington, Seattle, Washington 98195
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Lawrence Salkoff
1Departments of Anatomy and Neurobiology and
2Genetics, Washington University School of Medicine, St. Louis, Missouri 63110, and
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.20-20-07517.2000
PubMed 
11027209
Published By 
Society for Neuroscience
History 
  • Received April 14, 2000
  • Revision received July 18, 2000
  • Accepted July 26, 2000
  • First published October 15, 2000.
  • Version of record published October 15, 2000.
Copyright & Usage 
Copyright © 2000 Society for Neuroscience

Author Information

  1. Maya T. Kunkel1,
  2. Duncan B. Johnstone3,
  3. James H. Thomas3, and
  4. Lawrence Salkoff1,2
  1. 1Departments of Anatomy and Neurobiology and
  2. 2Genetics, Washington University School of Medicine, St. Louis, Missouri 63110, and
  3. 3Department of Genetics, University of Washington, Seattle, Washington 98195
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Author contributions

Disclosures

    • Received April 14, 2000.
    • Revision received July 18, 2000.
    • Accepted July 26, 2000.
  • This research was supported by grants to L.S. and J.H.T. from the National Institutes of Health. M.T.K. was supported by postdoctoral training grants from the McDonnell Center for Cellular and Molecular Neurobiology and the National Institutes of Health. We thank Danielle Thierry-Mieg for providing the e1913 allele and preliminary mapping data, and Mike Nonet and his laboratory for assistance in mapping the cn110 allele. We thank Dr. R. Horvitz for helpful discussions. We are grateful to members of our laboratories for helpful comments during the course of this work.

    The GenBank accession number for the twk-18 cDNA sequence is AF083650.

    Correspondence should be addressed to Dr. Lawrence Salkoff, Department of Anatomy and Neurobiology, Washington University, 660 South Euclid Avenue, Box 8108, St. Louis, MO 63110. E-mail:salkoffl{at}thalamus.wustl.edu.

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Total2151730704
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The Journal of Neuroscience: 20 (20)
Journal of Neuroscience
Vol. 20, Issue 20
15 Oct 2000
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Mutants of a Temperature-Sensitive Two-P Domain Potassium Channel
Maya T. Kunkel, Duncan B. Johnstone, James H. Thomas, Lawrence Salkoff
Journal of Neuroscience 15 October 2000, 20 (20) 7517-7524; DOI: 10.1523/JNEUROSCI.20-20-07517.2000

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Mutants of a Temperature-Sensitive Two-P Domain Potassium Channel
Maya T. Kunkel, Duncan B. Johnstone, James H. Thomas, Lawrence Salkoff
Journal of Neuroscience 15 October 2000, 20 (20) 7517-7524; DOI: 10.1523/JNEUROSCI.20-20-07517.2000
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Keywords

  • potassium channel
  • temperature
  • C. elegans
  • uncoordinated
  • mutant
  • TWIK
  • TASK
  • TREK
  • TRAAK
  • KCNK
  • unc-110
  • mah-2

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