Article Figures & Data
Figures
PVN αMSH and body energy balance. A, POMC mRNA was similar in sham (n = 10) and lesioned rats (n = 7) at all levels of the ARC that were analyzed. Each region (anterior, mid, posterior) is represented by the mean value from two sections per brain. B, Representative POMC autoradiographs of ARC in a sham and a lesioned rat in anterior ARC, both outlined by the template used in the analysis.C, The number of αMSH-positive varicosities in the PVN was decreased significantly in lesioned animals (n = 5) as compared with shams (n = 7; p = 0.037).D, Food intake (p = 0.0004) and weight gain (E; p = 0.005) were highly correlated to the number of αMSH-immunostained varicosities in the PVN in lesioned and sham rats. Open symbols, Sham rats; filled symbols, lesioned rats.