Skip to main content

Umbrella menu

  • SfN.org
  • eNeuro
  • The Journal of Neuroscience
  • Neuronline
  • BrainFacts.org

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
  • ALERTS
  • FOR AUTHORS
    • Preparing a Manuscript
    • Submission Guidelines
    • Fees
    • Journal Club
    • eLetters
    • Submit
  • EDITORIAL BOARD
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
  • SUBSCRIBE
  • SfN.org
  • eNeuro
  • The Journal of Neuroscience
  • Neuronline
  • BrainFacts.org

User menu

  • Log in
  • Subscribe
  • My alerts
  • My Cart

Search

  • Advanced search
Journal of Neuroscience
  • Log in
  • Subscribe
  • My alerts
  • My Cart
Journal of Neuroscience

Advanced Search

Submit a Manuscript
  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
  • ALERTS
  • FOR AUTHORS
    • Preparing a Manuscript
    • Submission Guidelines
    • Fees
    • Journal Club
    • eLetters
    • Submit
  • EDITORIAL BOARD
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
  • SUBSCRIBE
PreviousNext
ARTICLE, Cellular/Molecular

D2 Dopamine Receptors in Striatal Medium Spiny Neurons Reduce L-Type Ca2+ Currents and Excitability via a Novel PLCβ1–IP3–Calcineurin-Signaling Cascade

Salvador Hernández-López, Tatiana Tkatch, Enrique Perez-Garci, Elvira Galarraga, José Bargas, Heidi Hamm and D. James Surmeier
Journal of Neuroscience 15 December 2000, 20 (24) 8987-8995; DOI: https://doi.org/10.1523/JNEUROSCI.20-24-08987.2000
Salvador Hernández-López
1Department of Physiology and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tatiana Tkatch
1Department of Physiology and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Enrique Perez-Garci
2Instituto de Fisiologia Celular, UNAM Apartado Postal 70-253, Mexico DF 4510
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Elvira Galarraga
2Instituto de Fisiologia Celular, UNAM Apartado Postal 70-253, Mexico DF 4510
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
José Bargas
2Instituto de Fisiologia Celular, UNAM Apartado Postal 70-253, Mexico DF 4510
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Heidi Hamm
3Institute for Neuroscience, Northwestern University Medical School, Chicago, Illinois 60611, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
D. James Surmeier
1Department of Physiology and
3Institute for Neuroscience, Northwestern University Medical School, Chicago, Illinois 60611, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.20-24-08987.2000
PubMed 
11124974
Published By 
Society for Neuroscience
History 
  • Received July 25, 2000
  • Revision received September 15, 2000
  • Accepted September 21, 2000
  • First published December 15, 2000.
  • Version of record published December 15, 2000.
Copyright & Usage 
Copyright © 2000 Society for Neuroscience

Author Information

  1. Salvador Hernández-López1,
  2. Tatiana Tkatch1,
  3. Enrique Perez-Garci2,
  4. Elvira Galarraga2,
  5. José Bargas2,
  6. Heidi Hamm3, and
  7. D. James Surmeier1,3
  1. 1Department of Physiology and
  2. 3Institute for Neuroscience, Northwestern University Medical School, Chicago, Illinois 60611, and
  3. 2Instituto de Fisiologia Celular, UNAM Apartado Postal 70-253, Mexico DF 4510
View Full Text

Author contributions

Disclosures

    • Received July 25, 2000.
    • Revision received September 15, 2000.
    • Accepted September 21, 2000.
  • This work was supported by National Institutes of Health Grants NS 34696, DA 12958, and TW 01214 to D.J.S. and EY 10291 to H.H. Additional support was provided by Consejo Nacional de Ciencia y Tecnologia Grant 25812N to J.B. and E.G. We thank Sasha Ulrich for assistance with the RT-PCR experiments.

    Correspondence should be addressed to Dr. D. James Surmeier, Department of Physiology, Northwestern University Institute for Neuroscience, Northwestern University Medical School, 320 East Superior Street, Chicago, IL 60611. E-mail:j-surmeier{at}northwestern.edu.

Statistics from Altmetric.com

Article usage

Select a custom date range for the past year
E.g., 2021-03-01
to
E.g., 2021-03-01

Article usage: December 2000 to February 2021

AbstractFullPdf
Dec 20004512485
Total 20004512485
Jan 200197241183
Feb 2001118748
Mar 2001109668
Apr 2001125744
May 200174225
Jun 200135934
Jul 200143219
Aug 200143012
Sep 200153420
Oct 200193723
Nov 200154424
Dec 200132012
Total 2001170779512
Jan 200233121
Feb 200213330
Mar 200233521
Apr 200214556
May 200254341
Jun 200211516
Jul 200242426
Aug 200262224
Sep 200213536
Oct 200252420
Nov 200224434
Dec 200212416
Total 200233375341
Jan 200312820
Feb 200313931
Mar 200313126
Apr 200313429
May 200344033
Jun 200333224
Jul 200373015
Aug 2003103215
Sep 2003152917
Oct 2003223938
Nov 2003224433
Dec 2003153023
Total 2003102408304
Jan 2004214130
Feb 200493730
Mar 2004255825
Apr 2004194631
May 2004235620
Jun 2004165330
Jul 2004163418
Aug 2004394424
Sep 2004366532
Oct 2004306029
Nov 2004204221
Dec 2004305233
Total 2004284588323
Jan 2005344936
Feb 2005216222
Mar 2005498733
Apr 2005214728
May 2005203616
Jun 2005224028
Jul 2005113323
Aug 2005185219
Sep 2005135133
Oct 2005104329
Nov 2005143722
Dec 200583431
Total 2005241571320
Jan 2006124432
Feb 2006115043
Mar 2006154825
Apr 2006195030
May 2006143125
Jun 2006163921
Jul 2006103930
Aug 200694023
Sep 200693227
Oct 2006172720
Nov 2006133241
Dec 200672114
Total 2006152453331
Jan 2007154135
Feb 2007121715
Mar 2007153427
Apr 2007172524
May 2007124616
Jun 2007144231
Jul 2007112520
Aug 200793526
Sep 200792618
Oct 2007154528
Nov 2007152525
Dec 2007122116
Total 2007156382281
Jan 2008144525
Feb 2008104427
Mar 2008205433
Apr 2008362625
May 2008262823
Jun 2008123221
Jul 2008152326
Aug 2008322713
Sep 2008222721
Oct 2008343124
Nov 200822207
Dec 2008142532
Total 2008257382277
Jan 2009293924
Feb 2009171513
Mar 2009594030
Apr 2009211731
May 2009262528
Jun 2009121919
Jul 2009311618
Aug 2009191822
Sep 2009202433
Oct 2009161529
Nov 2009301515
Dec 2009212214
Total 2009301265276
Jan 2010324720
Feb 2010203130
Mar 2010283323
Apr 2010224920
May 2010195130
Jun 2010281618
Jul 2010213233
Aug 201091815
Sep 2010103118
Oct 2010184833
Nov 2010216329
Dec 2010152217
Total 2010243441286
Jan 2011341624
Feb 2011153327
Mar 2011273721
Apr 2011203339
May 2011233640
Jun 2011174050
Jul 2011122435
Aug 2011191630
Sep 2011102541
Oct 2011272539
Nov 2011132550
Dec 2011122334
Total 2011229333430
Jan 201271940
Feb 2012163053
Mar 2012282563
Apr 2012242476
May 2012152443
Jun 2012143443
Jul 2012202353
Aug 2012162341
Sep 201261644
Oct 2012182378
Nov 2012352062
Dec 201237738
Total 2012236268634
Jan 2013242050
Feb 2013252749
Mar 2013171846
Apr 2013331565
May 2013181457
Jun 2013192444
Jul 2013113069
Aug 2013202943
Sep 2013303355
Oct 2013233950
Nov 2013331051
Dec 201322945
Total 2013275268624
Jan 2014231131
Feb 2014212251
Mar 2014322463
Apr 2014243075
May 2014321461
Jun 2014342554
Jul 2014371652
Aug 2014251747
Sep 2014305854
Oct 2014274234
Nov 2014162448
Dec 2014231834
Total 2014324301604
Jan 2015233840
Feb 2015182434
Mar 2015333036
Apr 2015872550
May 2015431945
Jun 2015162625
Jul 2015181619
Aug 2015151820
Sep 2015322930
Oct 2015163435
Nov 201582432
Dec 2015455733
Total 2015354340399
Jan 2016343337
Feb 2016161520
Mar 2016325329
Apr 2016193944
May 2016215545
Jun 2016173331
Jul 2016273436
Aug 201693031
Sep 2016283926
Oct 201674724
Nov 201642737
Dec 201612315
Total 2016215428375
Jan 201793725
Feb 2017113717
Mar 2017155926
Apr 201773827
May 2017178327
Jun 2017113326
Jul 2017112726
Aug 2017112518
Sep 2017122823
Oct 2017123032
Nov 2017234526
Dec 201722518
Total 2017141467291
Jan 2018103023
Feb 2018154428
Mar 201894220
Apr 201883514
May 2018113817
Jun 201874820
Jul 201882314
Aug 201873719
Sep 2018103912
Oct 201893418
Nov 2018192722
Dec 201872114
Total 2018120418221
Jan 201974720
Feb 201984917
Mar 201994517
Apr 2019122432
May 201963320
Jun 201983014
Jul 201972726
Aug 2019144226
Sep 2019411916
Oct 20191622030
Nov 2019194826
Dec 2019122617
Total 2019122710261
Jan 2020103121
Feb 20205138
Mar 202072522
Apr 2020112720
May 2020173117
Jun 20207169
Jul 20204185
Aug 202072611
Sep 202073925
Oct 2020143811
Nov 202052811
Dec 2020142919
Total 2020108321179
Jan 202195313
Feb 202185639
Total 20211710952
Total412587317406
Back to top

In this issue

The Journal of Neuroscience: 20 (24)
Journal of Neuroscience
Vol. 20, Issue 24
15 Dec 2000
  • Table of Contents
  • Index by author
Email

Thank you for sharing this Journal of Neuroscience article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
D2 Dopamine Receptors in Striatal Medium Spiny Neurons Reduce L-Type Ca2+ Currents and Excitability via a Novel PLCβ1–IP3–Calcineurin-Signaling Cascade
(Your Name) has forwarded a page to you from Journal of Neuroscience
(Your Name) thought you would be interested in this article in Journal of Neuroscience.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Citation Tools
D2 Dopamine Receptors in Striatal Medium Spiny Neurons Reduce L-Type Ca2+ Currents and Excitability via a Novel PLCβ1–IP3–Calcineurin-Signaling Cascade
Salvador Hernández-López, Tatiana Tkatch, Enrique Perez-Garci, Elvira Galarraga, José Bargas, Heidi Hamm, D. James Surmeier
Journal of Neuroscience 15 December 2000, 20 (24) 8987-8995; DOI: 10.1523/JNEUROSCI.20-24-08987.2000

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Request Permissions
Share
D2 Dopamine Receptors in Striatal Medium Spiny Neurons Reduce L-Type Ca2+ Currents and Excitability via a Novel PLCβ1–IP3–Calcineurin-Signaling Cascade
Salvador Hernández-López, Tatiana Tkatch, Enrique Perez-Garci, Elvira Galarraga, José Bargas, Heidi Hamm, D. James Surmeier
Journal of Neuroscience 15 December 2000, 20 (24) 8987-8995; DOI: 10.1523/JNEUROSCI.20-24-08987.2000
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • neostriatum
  • patch clamp
  • dopamine
  • neuromodulation
  • medium spiny neuron
  • basal ganglia
  • electrophysiology
  • single-cell RT-PCR
  • ion channel
  • calcium

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

ARTICLE

  • Neural Correlates of Competing Fear Behaviors Evoked by an Innately Aversive Stimulus
  • Sp1 and Sp3 Are Oxidative Stress-Inducible, Antideath Transcription Factors in Cortical Neurons
  • Distinct Developmental Modes and Lesion-Induced Reactions of Dendrites of Two Classes of Drosophila Sensory Neurons
Show more ARTICLE

Cellular/Molecular

  • The GARP Domain of the Rod CNG Channel’s β1-subunit Contains Distinct Sites for Outer Segment Targeting and Connecting to the Photoreceptor Disc Rim
  • The phosphoprotein Synapsin Ia regulates the kinetics of dense-core vesicle release
  • Tuba Activates Cdc42 during Neuronal Polarization Downstream of the Small GTPase Rab8a
Show more Cellular/Molecular
  • Home
  • Alerts
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Issue Archive
  • Collections

Information

  • For Authors
  • For Advertisers
  • For the Media
  • For Subscribers

About

  • About the Journal
  • Editorial Board
  • Privacy Policy
  • Contact
  • Feedback
(JNeurosci logo)
(SfN logo)

Copyright © 2021 by the Society for Neuroscience.
JNeurosci Online ISSN: 1529-2401

The ideas and opinions expressed in JNeurosci do not necessarily reflect those of SfN or the JNeurosci Editorial Board. Publication of an advertisement or other product mention in JNeurosci should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in JNeurosci.