Article Figures & Data
Figures
- Fig. 1.
Effects of systemic injections of ifenprodil on LTM. A, Top, Outline of general behavioral procedures for pretraining systemic intraperitoneal injections of ifenprodil. Bottom, Mean (±SE) percentage freezing for tone and contextual LTM in rats injected with vehicle (n = 10), 1.0 mg/kg ifenprodil (n = 8), 3.0 mg/kg ifenprodil (n = 8), or 10.0 mg/kg ifenprodil (n = 8) before training. B,Top, Outline of general behavioral procedures for pretesting systemic intraperitoneal injections of ifenprodil.Bottom, Mean (±SE) percentage freezing for tone and contextual LTM in rats injected with vehicle (n = 10), 1.0 mg/kg ifenprodil (n = 8), 3.0 mg/kg ifenprodil (n = 8), or 10.0 mg/kg ifenprodil (n = 8) before testing. *p < 0.05 relative to vehicle.
- Fig. 2.
Effects of intra-amygdala infusions of ifenprodil on LTM. A, Top, Outline of general behavioral procedures for pretraining intra-amygdala infusions of ifenprodil for LTM testing only. Bottom, Mean (±SE) percentage freezing for tone and contextual LTM in rats given bilateral intra-amygdala infusions of vehicle (n = 10), 0.1 μg of ifenprodil (n = 6), or 1.0 μg of ifenprodil (n = 8) before training.B, Top, Outline of general behavioral procedures for pretesting intra-amygdala infusions of ifenprodil for LTM testing only. Bottom, Mean (±SE) percentage freezing for tone and contextual LTM in rats given bilateral intra-amygdala infusions of vehicle (n = 10), 0.1 μg of ifenprodil (n = 6), or 1.0 μg of ifenprodil (n = 8) before testing. *p < 0.05 relative to vehicle.
- Fig. 3.
Effects of intra-amygdala infusions of ifenprodil on STM and LTM. A, Top, Outline of general behavioral procedures for pretraining intra-amygdala infusions of ifenprodil for STM testing followed by LTM testing.Bottom, Mean (±SE) percentage freezing for tone (left) and contextual (right) STM and LTM in rats given bilateral intra-amygdala infusions of vehicle (n = 8), 0.1 μg of ifenprodil (n = 6), or 1.0 μg of ifenprodil (n = 8) before training. B,Top, Outline of general behavioral procedures for pretesting intra-amygdala infusions of ifenprodil for STM testing followed by LTM testing. Bottom, Mean (±SE) percentage freezing for tone (left) and contextual (right) STM and LTM in rats given bilateral intra-amygdala infusions of vehicle (n = 8), 0.1 μg of ifenprodil (n = 6), or 1.0 μg of ifenprodil (n = 8) before testing. *p < 0.05 relative to vehicle.
- Fig. 4.
Cannula placements. A, Cannula tip placements from rats infused with vehicle (asterisks), 0.1 μg of ifenprodil (circles), or 1.0 μg of ifenprodil (squares) before training (black) or before LTM testing only (gray). B, Cannula tip placements from rats infused with vehicle (asterisks), 0.1 μg of ifenprodil (circles), or 1.0 μg of ifenprodil (squares) before training (black) or before STM and LTM testing (gray).B, Basal nucleus; CE, central nucleus;LA, lateral nucleus.
