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ARTICLE, Behavioral/Systems

Hyperfunction of Dopaminergic and Serotonergic Neuronal Systems in Mice Lacking the NMDA Receptor ε1 Subunit

Yoshiaki Miyamoto, Kiyofumi Yamada, Yukihiro Noda, Hisashi Mori, Masayoshi Mishina and Toshitaka Nabeshima
Journal of Neuroscience 15 January 2001, 21 (2) 750-757; https://doi.org/10.1523/JNEUROSCI.21-02-00750.2001
Yoshiaki Miyamoto
1Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya 466-8560, Japan, and
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Kiyofumi Yamada
1Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya 466-8560, Japan, and
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Yukihiro Noda
1Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya 466-8560, Japan, and
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Hisashi Mori
2Department of Molecular Neurobiology and Pharmacology, School of Medicine, University of Tokyo, Tokyo 113-0033, Japan
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Masayoshi Mishina
2Department of Molecular Neurobiology and Pharmacology, School of Medicine, University of Tokyo, Tokyo 113-0033, Japan
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Toshitaka Nabeshima
1Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya 466-8560, Japan, and
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.21-02-00750.2001
PubMed 
11160454
Published By 
Society for Neuroscience
History 
  • Received May 24, 2000
  • Revision received October 30, 2000
  • Accepted November 3, 2000
  • First published January 15, 2001.
  • Version of record published January 15, 2001.
Copyright & Usage 
Copyright © 2001 Society for Neuroscience

Author Information

  1. Yoshiaki Miyamoto1,
  2. Kiyofumi Yamada1,
  3. Yukihiro Noda1,
  4. Hisashi Mori2,
  5. Masayoshi Mishina2, and
  6. Toshitaka Nabeshima1
  1. 1Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya 466-8560, Japan, and
  2. 2Department of Molecular Neurobiology and Pharmacology, School of Medicine, University of Tokyo, Tokyo 113-0033, Japan
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Author contributions

Disclosures

    • Received May 24, 2000.
    • Revision received October 30, 2000.
    • Accepted November 3, 2000.
  • This work was supported in part by a Grant-in-Aid for Scientific Research (10044260) and COE Research from the Ministry of Education, Science, Sports, and Culture of Japan, by the Health Sciences Research Grants for Research on Pharmaceutical and Medical Safety from the Ministry of Health and Welfare of Japan, and by Special Coordination Funds for Promoting Science and Technology, Target-Oriented Brain Science Research Program from the Ministry of Science and Technology of Japan.

    Correspondence should be addressed to Dr. Toshitaka Nabeshima, Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya 466-8560, Japan. E-mail: tnabeshi{at}med.nagoya-u.ac.jp.

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The Journal of Neuroscience: 21 (2)
Journal of Neuroscience
Vol. 21, Issue 2
15 Jan 2001
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Hyperfunction of Dopaminergic and Serotonergic Neuronal Systems in Mice Lacking the NMDA Receptor ε1 Subunit
Yoshiaki Miyamoto, Kiyofumi Yamada, Yukihiro Noda, Hisashi Mori, Masayoshi Mishina, Toshitaka Nabeshima
Journal of Neuroscience 15 January 2001, 21 (2) 750-757; DOI: 10.1523/JNEUROSCI.21-02-00750.2001

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Hyperfunction of Dopaminergic and Serotonergic Neuronal Systems in Mice Lacking the NMDA Receptor ε1 Subunit
Yoshiaki Miyamoto, Kiyofumi Yamada, Yukihiro Noda, Hisashi Mori, Masayoshi Mishina, Toshitaka Nabeshima
Journal of Neuroscience 15 January 2001, 21 (2) 750-757; DOI: 10.1523/JNEUROSCI.21-02-00750.2001
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Keywords

  • NMDA receptor
  • GluRε1 subunit
  • dopaminergic neuronal system
  • serotonergic neuronal system
  • hyperlocomotion
  • schizophrenia

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