Article Figures & Data
Figures
- Fig. 1.
Use of DNA arrays to examine dendrite molecular biology. A schematizes the harvesting of hippocampal tissue for use in isolation of polysomes and the array result.B shows the harvesting of dendrites and a cell soma (indicated by arrows) using a microelectrode as a scalpel. After DHPG treatment, the dendrites are microdissected and an aRNA probe is synthesized; this probe was used to probe a homemade macroarray shown in B.
- Fig. 2.
Microdissection of the mouse amygdala and macroarray analysis of subregions. Sections through the mouse brain were stained with cresyl violet to visualize subregions of the amygdala for dissection. Neuroarray hybridization results are shown for the basolateral and central nuclei. Arrows highlight cDNAs for which mRNA abundances differ between basolateral and control nuclei.
- Fig. 3.
mRNA expression analysis of dying cells in traumatic brain injury. The arrows in A show a cell of the CA3 region of the hippocampus that is caspase-3-positive and TUNEL-positive after TBI. aRNA probes were fluorescently labeled and applied to an Incyte (Palo Alto, CA) Gem microarray, a portion of which is shown in B. The scattergram of these array results is shown in C.
