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ARTICLE, Behavioral/Systems

bcl-2 Overexpression Eliminates Deprivation-Induced Cell Death of Brainstem Auditory Neurons

Sam P. Mostafapour, N. Mae del Puerto and Edwin W Rubel
Journal of Neuroscience 1 June 2002, 22 (11) 4670-4674; DOI: https://doi.org/10.1523/JNEUROSCI.22-11-04670.2002
Sam P. Mostafapour
1Virginia Merrill Bloedel Hearing Research Center and Department of Otolaryngology, Head and Neck Surgery, University of Washington, Seattle, Washington 98195
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N. Mae del Puerto
1Virginia Merrill Bloedel Hearing Research Center and Department of Otolaryngology, Head and Neck Surgery, University of Washington, Seattle, Washington 98195
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Edwin W Rubel
1Virginia Merrill Bloedel Hearing Research Center and Department of Otolaryngology, Head and Neck Surgery, University of Washington, Seattle, Washington 98195
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.22-11-04670.2002
PubMed 
12040073
Published By 
Society for Neuroscience
History 
  • Received May 17, 2001
  • Revision received March 1, 2002
  • Accepted March 7, 2002
  • First published June 1, 2002.
  • Version of record published June 1, 2002.
Copyright & Usage 
Copyright © 2002 Society for Neuroscience

Author Information

  1. Sam P. Mostafapour,
  2. N. Mae del Puerto, and
  3. Edwin W Rubel
  1. 1Virginia Merrill Bloedel Hearing Research Center and Department of Otolaryngology, Head and Neck Surgery, University of Washington, Seattle, Washington 98195
View Full Text

Author contributions

Disclosures

    • Received May 17, 2001.
    • Revision received March 1, 2002.
    • Accepted March 7, 2002.
  • This work was supported by National Institutes of Health Grant DC03829. We thank Dr. Dong-Feng Chen for providingbcl-2-overexpressing mice and Dr. Virginia Lee for anti-α-neurofilament antibody.

  • Correspondence should be addressed to Edwin W Rubel, Virginia Merrill Bloedel Hearing Research Center, Box 357923, CHDD Building, Room CD176, University of Washington, Seattle, WA 98195. E-mail:rubel{at}u.washington.edu.

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The Journal of Neuroscience: 22 (11)
Journal of Neuroscience
Vol. 22, Issue 11
1 Jun 2002
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bcl-2 Overexpression Eliminates Deprivation-Induced Cell Death of Brainstem Auditory Neurons
Sam P. Mostafapour, N. Mae del Puerto, Edwin W Rubel
Journal of Neuroscience 1 June 2002, 22 (11) 4670-4674; DOI: 10.1523/JNEUROSCI.22-11-04670.2002

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bcl-2 Overexpression Eliminates Deprivation-Induced Cell Death of Brainstem Auditory Neurons
Sam P. Mostafapour, N. Mae del Puerto, Edwin W Rubel
Journal of Neuroscience 1 June 2002, 22 (11) 4670-4674; DOI: 10.1523/JNEUROSCI.22-11-04670.2002
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Keywords

  • deafferentation
  • Bcl-2
  • caspase-3
  • apoptosis
  • cochlear nucleus
  • critical period

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