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Release of Hypocretin (Orexin) during Waking and Sleep States

Lyudmila I. Kiyashchenko, Boris Y. Mileykovskiy, Nigel Maidment, Hoa A. Lam, Ming-Fung Wu, Joshi John, John Peever and Jerome M. Siegel
Journal of Neuroscience 1 July 2002, 22 (13) 5282-5286; https://doi.org/10.1523/JNEUROSCI.22-13-05282.2002
Lyudmila I. Kiyashchenko
1Department of Psychiatry and Biobehavioral Sciences and Brain Research Institute, University of California Los Angeles School of Medicine, and
2Veterans Administration of Greater Los Angeles Healthcare System-Sepulveda, North Hills, California 91343, and
3Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Science, St. Petersburg, 194223, Russia
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Boris Y. Mileykovskiy
1Department of Psychiatry and Biobehavioral Sciences and Brain Research Institute, University of California Los Angeles School of Medicine, and
2Veterans Administration of Greater Los Angeles Healthcare System-Sepulveda, North Hills, California 91343, and
3Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Science, St. Petersburg, 194223, Russia
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Nigel Maidment
1Department of Psychiatry and Biobehavioral Sciences and Brain Research Institute, University of California Los Angeles School of Medicine, and
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Hoa A. Lam
1Department of Psychiatry and Biobehavioral Sciences and Brain Research Institute, University of California Los Angeles School of Medicine, and
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Ming-Fung Wu
1Department of Psychiatry and Biobehavioral Sciences and Brain Research Institute, University of California Los Angeles School of Medicine, and
2Veterans Administration of Greater Los Angeles Healthcare System-Sepulveda, North Hills, California 91343, and
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Joshi John
1Department of Psychiatry and Biobehavioral Sciences and Brain Research Institute, University of California Los Angeles School of Medicine, and
2Veterans Administration of Greater Los Angeles Healthcare System-Sepulveda, North Hills, California 91343, and
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John Peever
1Department of Psychiatry and Biobehavioral Sciences and Brain Research Institute, University of California Los Angeles School of Medicine, and
2Veterans Administration of Greater Los Angeles Healthcare System-Sepulveda, North Hills, California 91343, and
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Jerome M. Siegel
1Department of Psychiatry and Biobehavioral Sciences and Brain Research Institute, University of California Los Angeles School of Medicine, and
2Veterans Administration of Greater Los Angeles Healthcare System-Sepulveda, North Hills, California 91343, and
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.22-13-05282.2002
PubMed 
12097478
Published By 
Society for Neuroscience
History 
  • Received February 27, 2002
  • Revision received April 4, 2002
  • Accepted April 9, 2002
  • First published July 1, 2002.
  • Version of record published July 1, 2002.
Copyright & Usage 
Copyright © 2002 Society for Neuroscience

Author Information

  1. Lyudmila I. Kiyashchenko1,2,3,*,
  2. Boris Y. Mileykovskiy1,2,3,*,
  3. Nigel Maidment1,
  4. Hoa A. Lam1,
  5. Ming-Fung Wu1,2,
  6. Joshi John1,2,
  7. John Peever1,2, and
  8. Jerome M. Siegel1,2
  1. 1Department of Psychiatry and Biobehavioral Sciences and Brain Research Institute, University of California Los Angeles School of Medicine, and
  2. 2Veterans Administration of Greater Los Angeles Healthcare System-Sepulveda, North Hills, California 91343, and
  3. 3Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Science, St. Petersburg, 194223, Russia
View Full Text

Author contributions

Disclosures

    • Received February 27, 2002.
    • Revision received April 4, 2002.
    • Accepted April 9, 2002.
  • ↵* L.I.K. and B.Y.M., contributed equally to this study.

  • This work was supported by National Institutes of Health Grants MH64109 and NS14610 and by the Medical Research Service of the Department of Veterans Affairs.

  • Correspondence should be addressed to Jerome Siegel, Department of Psychiatry, University of California Los Angeles, Neurobiology Res. 151A3, Veterans Adminstration of Greater Los Angeles Healthcare System, 16111 Plummer Street, North Hills, CA 91343. E-mail:JSiegel{at}UCLA.edu.

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Jan 20183179
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Total 202561575173
Total60231421073
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The Journal of Neuroscience: 22 (13)
Journal of Neuroscience
Vol. 22, Issue 13
1 Jul 2002
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Release of Hypocretin (Orexin) during Waking and Sleep States
Lyudmila I. Kiyashchenko, Boris Y. Mileykovskiy, Nigel Maidment, Hoa A. Lam, Ming-Fung Wu, Joshi John, John Peever, Jerome M. Siegel
Journal of Neuroscience 1 July 2002, 22 (13) 5282-5286; DOI: 10.1523/JNEUROSCI.22-13-05282.2002

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Release of Hypocretin (Orexin) during Waking and Sleep States
Lyudmila I. Kiyashchenko, Boris Y. Mileykovskiy, Nigel Maidment, Hoa A. Lam, Ming-Fung Wu, Joshi John, John Peever, Jerome M. Siegel
Journal of Neuroscience 1 July 2002, 22 (13) 5282-5286; DOI: 10.1523/JNEUROSCI.22-13-05282.2002
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Keywords

  • hypocretin
  • orexin
  • microdialysis
  • sleep–waking cycle
  • motor activity
  • cataplexy

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