Article Figures & Data
Figures
- Fig. 1.
Sleep-cycle release of Hcrt. A–C, Location of the tips of dialysis probes in the HYP, BF, and LC.CI, Internal capsule; CO, optic chasm;f, fornix; LH, lateral hypothalamus.D–F, Hcrt levels across the sleep–waking states in the HYP, BF, and LC. Sleep-state values differ as a function of state (HYP,p < 0.003, F = 4.7, df = 3254; BF, p < 0.03, F = 3.2, df = 3133). Tukey's test; *p < 0.05; **p < 0.02; ***p < 0.002. Hcrt release is maximal during AW and REM sleep and minimal during SWS and QW in the HYP and BF.
- Fig. 2.
Hypnogram (A) and Hcrt levels (B) in the HYP across the sleep cycle. Circles indicate points at which dialysate was taken. Hcrt levels are maximal after long AW and REM sleep periods and minimal after SWS periods.
- Fig. 3.
Concentrations of Hcrt-1 in the CSF during AW and QW. Left, Actigraph readings reflect greater levels of head movement during active waking. Right, Hcrt levels are significantly higher in CSF taken after a 2 hr AW period than after a 2 hr QW period. **p < 0.02;t = 3.4; df = 5.
