Skip to main content

Umbrella menu

  • SfN.org
  • eNeuro
  • The Journal of Neuroscience
  • Neuronline
  • BrainFacts.org

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
  • ALERTS
  • FOR AUTHORS
    • Preparing a Manuscript
    • Submission Guidelines
    • Fees
    • Journal Club
    • eLetters
    • Submit
  • EDITORIAL BOARD
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
  • SUBSCRIBE
  • SfN.org
  • eNeuro
  • The Journal of Neuroscience
  • Neuronline
  • BrainFacts.org

User menu

  • Log out
  • Log in
  • Subscribe
  • My alerts

Search

  • Advanced search
Journal of Neuroscience
  • Log out
  • Log in
  • Subscribe
  • My alerts
Journal of Neuroscience

Advanced Search

Submit a Manuscript
  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
  • ALERTS
  • FOR AUTHORS
    • Preparing a Manuscript
    • Submission Guidelines
    • Fees
    • Journal Club
    • eLetters
    • Submit
  • EDITORIAL BOARD
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
  • SUBSCRIBE
PreviousNext
BRIEF COMMUNICATION

Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease

Linda A. Kotilinek, Brian Bacskai, Marcus Westerman, Takeshi Kawarabayashi, Linda Younkin, Bradley T. Hyman, Steven Younkin and Karen H. Ashe
Journal of Neuroscience 1 August 2002, 22 (15) 6331-6335; DOI: https://doi.org/10.1523/JNEUROSCI.22-15-06331.2002
Linda A. Kotilinek
1Departments of Neurology and Neuroscience, University of Minnesota, Minneapolis 55455,
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Brian Bacskai
2Department of Neurology, Massachusetts General Hospital East, Charlestown, Massachusetts 02129, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marcus Westerman
1Departments of Neurology and Neuroscience, University of Minnesota, Minneapolis 55455,
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Takeshi Kawarabayashi
3Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Linda Younkin
3Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Bradley T. Hyman
2Department of Neurology, Massachusetts General Hospital East, Charlestown, Massachusetts 02129, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Steven Younkin
3Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Karen H. Ashe
1Departments of Neurology and Neuroscience, University of Minnesota, Minneapolis 55455,
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.22-15-06331.2002
PubMed 
12151510
Published By 
Society for Neuroscience
History 
  • Received April 1, 2002
  • Revision received May 10, 2002
  • Accepted May 20, 2002
  • First published August 1, 2002.
  • Version of record published August 1, 2002.
Copyright & Usage 
Copyright © 2002 Society for Neuroscience

Author Information

  1. Linda A. Kotilinek1,
  2. Brian Bacskai2,
  3. Marcus Westerman1,
  4. Takeshi Kawarabayashi3,
  5. Linda Younkin3,
  6. Bradley T. Hyman2,
  7. Steven Younkin3, and
  8. Karen H. Ashe1
  1. 1Departments of Neurology and Neuroscience, University of Minnesota, Minneapolis 55455,
  2. 2Department of Neurology, Massachusetts General Hospital East, Charlestown, Massachusetts 02129, and
  3. 3Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224
View Full Text

Author contributions

View Abstract

Disclosures

    • Received April 1, 2002.
    • Revision received May 10, 2002.
    • Accepted May 20, 2002.
  • This work was supported by National Institutes of Health Grants AG15453 (K.H.A., B.T.H., S.Y.), NS33249 (K.H.A.), MH65465 (K.H.A.), and AG08687 (B.T.H.); by a Pioneer Award from the Alzheimer's Association (B.T.H.); and by The Walter Family Foundation (B.T.H.). We gratefully acknowledge Stefanie Schrump, Deirdre Cooper-Blacketer, Jennifer Perry, Aaron Guimaraes, Jennifer Lang, Jennifer Paulson, and Nardina Nash for their expertise and dedication testing mice in the water maze. We thank Megan McLellan and Steve Kajdasz for technical assistance with immunohistological procedures and Eugene Gnida for technical help performing ELISAs.

  • Correspondence should be addressed to Karen H. Ashe, Department of Neurology, Mayo Mail Code 295, 420 Delaware Street Southeast, Minneapolis, MN 55455. E-mail: hsiao005{at}umn.edu.

  • T. Kawarabayashi's present address: Department of Neurology, Okayama University Graduate School of Medicine, Okayama, 700-8558 Japan.

Statistics from Altmetric.com

Article usage

Select a custom date range for the past year
E.g., 2021-01-25
to
E.g., 2021-01-25

Article usage: July 2002 to January 2021

AbstractFullPdf
Jul 2002641446
Aug 200214674441265
Sep 200254169181
Oct 200250135127
Nov 2002199474
Dec 2002225346
Total 200216769091739
Jan 2003156469
Feb 2003147060
Mar 2003186256
Apr 2003117351
May 200386343
Jun 200373539
Jul 200395954
Aug 2003134044
Sep 2003244037
Oct 2003237064
Nov 2003204750
Dec 2003205445
Total 2003182677612
Jan 2004186046
Feb 2004164041
Mar 2004345043
Apr 2004205140
May 2004226557
Jun 2004186951
Jul 2004255356
Aug 2004427832
Sep 2004406356
Oct 2004267340
Nov 2004206648
Dec 2004245332
Total 2004305721542
Jan 2005287239
Feb 2005405852
Mar 2005436147
Apr 2005177558
May 2005304841
Jun 2005194727
Jul 2005346357
Aug 2005286250
Sep 2005106335
Oct 2005228949
Nov 2005197949
Dec 2005166947
Total 2005306786551
Jan 2006168148
Feb 2006135537
Mar 2006359140
Apr 2006219358
May 2006226338
Jun 2006154723
Jul 200694028
Aug 2006184729
Sep 20061815645
Oct 20063610546
Nov 20063011271
Dec 2006287239
Total 2006261962502
Jan 2007367756
Feb 2007347647
Mar 2007517646
Apr 20074310655
May 2007267838
Jun 2007177238
Jul 2007144132
Aug 2007204433
Sep 2007215135
Oct 2007386451
Nov 2007265245
Dec 2007215641
Total 2007347793517
Jan 2008155746
Feb 2008376447
Mar 2008214636
Apr 2008275744
May 2008194331
Jun 2008326843
Jul 2008193227
Aug 2008314219
Sep 2008464044
Oct 2008293938
Nov 2008404631
Dec 2008175631
Total 2008333590437
Jan 2009213526
Feb 20093215331
Mar 2009436042
Apr 2009445344
May 2009243128
Jun 2009163631
Jul 2009261912
Aug 2009131816
Sep 2009263032
Oct 2009292424
Nov 2009494757
Dec 2009333134
Total 2009356537377
Jan 2010323422
Feb 2010284329
Mar 2010355254
Apr 2010283720
May 2010196437
Jun 2010263943
Jul 2010143927
Aug 2010162721
Sep 2010233221
Oct 2010223824
Nov 2010262617
Dec 2010313427
Total 2010300465342
Jan 2011272318
Feb 2011282521
Mar 2011393428
Apr 2011351829
May 2011363538
Jun 2011253329
Jul 2011151723
Aug 2011232325
Sep 2011432419
Oct 2011543325
Nov 2011542547
Dec 2011353326
Total 2011414323328
Jan 2012262725
Feb 2012293228
Mar 2012495136
Apr 2012463726
May 2012323341
Jun 2012181915
Jul 2012163023
Aug 2012202030
Sep 2012141646
Oct 2012473258
Nov 2012581946
Dec 2012411227
Total 2012396328401
Jan 2013352134
Feb 2013411734
Mar 2013393857
Apr 2013502245
May 2013331842
Jun 2013241424
Jul 2013131030
Aug 2013172332
Sep 2013311522
Oct 2013383039
Nov 2013514045
Dec 2013501741
Total 2013422265445
Jan 2014233049
Feb 2014282047
Mar 2014672666
Apr 2014715084
May 2014551973
Jun 2014391759
Jul 2014362880
Aug 2014191081
Sep 2014672149
Oct 2014382837
Nov 2014703427
Dec 2014632132
Total 2014576304684
Jan 2015222736
Feb 2015402645
Mar 2015791828
Apr 2015632839
May 2015401126
Jun 2015662425
Jul 2015291025
Aug 2015201117
Sep 20152231422
Oct 2015781932
Nov 2015612624
Dec 2015461713
Total 2015767231332
Jan 2016502137
Feb 2016412721
Mar 2016714146
Apr 2016351613
May 2016451926
Jun 201628810
Jul 2016182016
Aug 2016241625
Sep 2016401515
Oct 2016406314
Nov 2016693737
Dec 2016423316
Total 2016503316276
Jan 2017291710
Feb 2017222420
Mar 2017262918
Apr 2017331759
May 2017317631
Jun 201714139
Jul 201721144
Aug 20179168
Sep 201717197
Oct 2017523228
Nov 2017434522
Dec 2017332314
Total 2017330325230
Jan 201817276
Feb 201873312
Mar 2018584
Apr 20189173
May 20184195
Jun 20184243
Jul 2018191818
Aug 2018161713
Sep 2018243515
Oct 2018384737
Nov 2018503223
Dec 2018245121
Total 2018217328160
Jan 2019224221
Feb 2019262535
Mar 2019295630
Apr 2019264118
May 2019393918
Jun 2019112311
Jul 2019121819
Aug 2019142024
Sep 201981812
Oct 2019355026
Nov 2019262626
Dec 2019143610
Total 2019262394250
Jan 2020161611
Feb 2020352326
Mar 202019198
Apr 2020281627
May 2020161310
Jun 20201369
Jul 202011154
Aug 20209173
Sep 2020253939
Oct 2020233216
Nov 2020324134
Dec 2020395235
Total 2020266289222
Jan 2021214529
Total 2021214529
Total824095888976
Back to top

In this issue

The Journal of Neuroscience: 22 (15)
Journal of Neuroscience
Vol. 22, Issue 15
1 Aug 2002
  • Table of Contents
  • Index by author
Email

Thank you for sharing this Journal of Neuroscience article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease
(Your Name) has forwarded a page to you from Journal of Neuroscience
(Your Name) thought you would be interested in this article in Journal of Neuroscience.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Citation Tools
Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease
Linda A. Kotilinek, Brian Bacskai, Marcus Westerman, Takeshi Kawarabayashi, Linda Younkin, Bradley T. Hyman, Steven Younkin, Karen H. Ashe
Journal of Neuroscience 1 August 2002, 22 (15) 6331-6335; DOI: 10.1523/JNEUROSCI.22-15-06331.2002

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Request Permissions
Share
Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease
Linda A. Kotilinek, Brian Bacskai, Marcus Westerman, Takeshi Kawarabayashi, Linda Younkin, Bradley T. Hyman, Steven Younkin, Karen H. Ashe
Journal of Neuroscience 1 August 2002, 22 (15) 6331-6335; DOI: 10.1523/JNEUROSCI.22-15-06331.2002
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • Alzheimer's disease
  • transgenic
  • behavior
  • Aβ
  • monoclonal antibodies
  • memory

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

  • Inter-regional Contribution of Enhanced Activity of the Primary Somatosensory Cortex to the Anterior Cingulate Cortex Accelerates Chronic Pain Behavior
  • MrgD Activation Inhibits KCNQ/M-Currents and Contributes to Enhanced Neuronal Excitability
  • Dopaminergic Substantia Nigra Neurons Project Topographically Organized to the Subventricular Zone and Stimulate Precursor Cell Proliferation in Aged Primates
Show more Brief Communication
  • Home
  • Alerts
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Issue Archive
  • Collections

Information

  • For Authors
  • For Advertisers
  • For the Media
  • For Subscribers

About

  • About the Journal
  • Editorial Board
  • Privacy Policy
  • Contact
  • Feedback
(JNeurosci logo)
(SfN logo)

Copyright © 2021 by the Society for Neuroscience.
JNeurosci Online ISSN: 1529-2401

The ideas and opinions expressed in JNeurosci do not necessarily reflect those of SfN or the JNeurosci Editorial Board. Publication of an advertisement or other product mention in JNeurosci should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in JNeurosci.