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ARTICLE, Development/Plasticity/Repair

Identification of Domains of Netrin UNC-6 that Mediate Attractive and Repulsive Guidance and Responses from Cells and Growth Cones

Yoo-shick Lim and William G. Wadsworth
Journal of Neuroscience 15 August 2002, 22 (16) 7080-7087; https://doi.org/10.1523/JNEUROSCI.22-16-07080.2002
Yoo-shick Lim
1Department of Pathology, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854-5635
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William G. Wadsworth
1Department of Pathology, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854-5635
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.22-16-07080.2002
PubMed 
12177204
Published By 
Society for Neuroscience
History 
  • Received March 6, 2002
  • Revision received May 1, 2002
  • Accepted May 9, 2002
  • First published August 15, 2002.
  • Version of record published August 15, 2002.
Copyright & Usage 
Copyright © 2002 Society for Neuroscience

Author Information

  1. Yoo-shick Lim and
  2. William G. Wadsworth
  1. 1Department of Pathology, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854-5635
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Author contributions

Disclosures

    • Received March 6, 2002.
    • Revision received May 1, 2002.
    • Accepted May 9, 2002.
  • This work was supported by National Institutes of Health Grant NS33156. We thank Christopher Quinn for comments on this manuscript, members of the Wadsworth laboratory for helpful discussions, Xing-Cong Ren for assistance with microinjection, the Caenorhabditis Genetics Center for strains, and Joseph Culotti, Edward Hedgecock, Harold Hutter, and David Pilgrim for generously providing GFP marker strains.

  • Correspondence should be addressed to William G. Wadsworth, Department of Pathology, Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854-5635. E-mail:william.wadsworth{at}umdnj.edu.

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The Journal of Neuroscience: 22 (16)
Journal of Neuroscience
Vol. 22, Issue 16
15 Aug 2002
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Identification of Domains of Netrin UNC-6 that Mediate Attractive and Repulsive Guidance and Responses from Cells and Growth Cones
Yoo-shick Lim, William G. Wadsworth
Journal of Neuroscience 15 August 2002, 22 (16) 7080-7087; DOI: 10.1523/JNEUROSCI.22-16-07080.2002

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Identification of Domains of Netrin UNC-6 that Mediate Attractive and Repulsive Guidance and Responses from Cells and Growth Cones
Yoo-shick Lim, William G. Wadsworth
Journal of Neuroscience 15 August 2002, 22 (16) 7080-7087; DOI: 10.1523/JNEUROSCI.22-16-07080.2002
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Keywords

  • netrin
  • UNC-6
  • C. elegans
  • axon guidance
  • cell migration
  • structure–function

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